Transudation (/ˌtrænzjʊˈdeɪʃən/) is spelled with a 't', 'r', 'a', 'n', 's', 'u', 'd', 'a', 't', 'i', 'o', and 'n'. The word refers to the process of fluid passing through a membrane or tissue due to a difference in pressure. The correct spelling of this word can be verified with the International Phonetic Alphabet (IPA) transcription, which shows the pronunciation of each letter or syllable in the word. The phonetic transcription highlights the proper pronunciation of the word to avoid any spelling errors.
Transudation refers to the process through which a fluid, typically blood serum, passes through vessel walls into surrounding tissues or spaces due to a passive mechanism. It occurs primarily due to alterations in hydrostatic pressure, osmotic pressure, or permeability of blood vessels. This phenomenon is distinct from exudation, which involves a more active or inflammatory response resulting in the leakage of cells and proteins from blood vessels.
In transudation, the fluid that moves from the intravascular space to the extravascular space is usually clear, containing minimal cellular elements and proteins. This fluid transfer occurs across normal or slightly altered vessel walls, exerting minimal or no cellular or inflammatory response.
Transudation commonly arises from imbalances in intravascular pressures, such as increased hydrostatic pressure or decreased oncotic pressure. For example, conditions like heart failure, liver disease, or kidney disease can cause fluid to accumulate in tissues due to increased capillary hydrostatic pressure. In contrast, reduced plasma oncotic pressure, seen in situations like nephrotic syndrome or malnutrition, may lead to a movement of fluid into tissues.
The measurement of protein content and specific gravity of the fluid can help distinguish transudate from exudate. In clinical diagnostics, transudation may aid in the identification and understanding of various pathological conditions, aiding in the diagnosis and appropriate treatment of patients.
The passage of a fluid through a membrane; diapedesis. It differs from osmosis in that the fluid passes with nearly all the salts and other substances held in solution or suspension, and from exudation in that all the solids do not pass to the same extent.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The oozing of fluids or vapours through porous bodies.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.
The word "transudation" is derived from the Latin term "transudatio", which comes from the verb "transudare". "Transudare" is a combination of the prefix "trans-" meaning "across" or "through", and the verb "udare" meaning "to be wet". Therefore, "transudation" can be understood as the act of something passing or seeping through, especially referring to the movement of fluid through a membrane or permeable substance.