MURINE MODEL Meaning and
Definition
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A murine model refers to a laboratory experimental system that involves the use of mice for studying biological processes and diseases that are relevant to humans. The term "murine" specifically denotes anything related to mice, which are small rodents commonly found in various regions of the world.
Murine models have become instrumental tools in biomedical research due to their genetic similarity to humans, as mice share approximately 95% of their genome with humans. By manipulating the mouse genome, scientists can simulate human conditions and investigate the underlying mechanisms of diseases, as well as evaluate potential treatments and therapies. Researchers extensively use murine models to study a wide range of health conditions, including cancer, cardiovascular diseases, infectious diseases, neurological disorders, and immunology.
When establishing a murine model, scientists often introduce specific genetic modifications in mice using techniques like gene editing, transgenesis, or knockout technology. These modifications allow researchers to mimic human diseases or traits, providing valuable insights into the complex interactions between genes, environmental factors, and diseases.
Murine models offer several advantages over other animal models due to their cost-effectiveness, reproductive capabilities, short gestation period, and relatively small size, making them easier to handle and maintain. Moreover, their genetic similarity to humans enables the translation of findings from murine studies to clinical applications, contributing to the development of new diagnostics, drugs, and therapies.
Common Misspellings for MURINE MODEL
- nurine model
- kurine model
- jurine model
- myrine model
- mhrine model
- mjrine model
- mirine model
- m8rine model
- m7rine model
- mueine model
- mudine model
- mufine model
- mutine model
- mu5ine model
- mu4ine model
- murune model
- murjne model
- murkne model
- murone model
- mur9ne model
Etymology of MURINE MODEL
The term murine model comes from the word murine which means of or relating to mice and the word model which refers to a representation or simulation of a particular system or phenomenon. In the context of biomedical research, a murine model typically refers to the use of mice as experimental subjects to study human diseases or physiological processes. The term originated from Latin, where murinus means of a mouse or mouse-like.
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