IMMUNOPHENOTYPING Meaning and
Definition
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Immunophenotyping refers to a laboratory technique used in the field of immunology to identify and classify different types of cells within a biological sample based on their specific protein markers or antigens present on their surface or inside the cells. This technique serves as a powerful tool to characterize and understand the cellular composition of various tissues or blood samples.
Through immunophenotyping, scientists can determine the specific types of immune cells present in a sample, such as lymphocytes (T cells, B cells, and natural killer cells), granulocytes, monocytes, or dendritic cells. By analyzing the expression and combination of different cell surface markers using specific antibodies, the immunophenotyping technique provides valuable insights into the functional state and identity of different cell populations.
Immunophenotyping requires the use of flow cytometry, a technology that enables the simultaneous detection of multiple cell surface markers on individual cells. This technique involves the labeling of cells with fluorescently tagged antibodies that specifically bind to the target antigens of interest. As the labeled cells pass through a flow cytometer, a laser excites the fluorochromes attached to the cells, resulting in the emission of light at different wavelengths. The emitted light is then detected and measured, providing information about the relative abundance and characteristics of different cell populations within a sample.
Immunophenotyping has extensive applications in clinical diagnostics and research, aiding in the diagnosis and monitoring of various diseases, including cancers, autoimmune disorders, and immunodeficiencies. It helps in assessing immune responses, identifying abnormal cell populations, monitoring treatment effectiveness, and understanding the immune system's role in various conditions.
Common Misspellings for IMMUNOPHENOTYPING
- ummunophenotyping
- jmmunophenotyping
- kmmunophenotyping
- ommunophenotyping
- 9mmunophenotyping
- 8mmunophenotyping
- inmunophenotyping
- ikmunophenotyping
- ijmunophenotyping
- imnunophenotyping
- imkunophenotyping
- imjunophenotyping
- immynophenotyping
- immhnophenotyping
- immjnophenotyping
- imminophenotyping
- imm8nophenotyping
- imm7nophenotyping
- immubophenotyping
- immumophenotyping
Etymology of IMMUNOPHENOTYPING
The term "immunophenotyping" is derived from two main components: "immuno" and "phenotyping".
1. "Immun(o)": This part of the word is derived from the Greek word "immūn" (ἰμμῡν) meaning "exempt". It is also linked to the Latin term "immunis", which carries the meaning of "protected" or "exempt from duty or service". In modern usage, "immuno" is related to "immune", referring to the body's defense system against diseases and foreign substances.
2. "Phenotyping": This part is derived from the word "phenotype", which has its roots in genetics and biology. "Phenotype" originated from the Greek word "phainómenon" (φαινόμενον), which means "appearing" or "visible".
