Granuloma sarcomatodes is a medical term used to describe a type of inflammation in the body that can lead to cancer. The spelling of this word can be tricky due to the combination of three consonants in a row. The pronunciation is as follows: /ɡrænjəˈloʊmə sɑːrkəˈmoʊtoʊdiːz/. The first syllable, "gran," is pronounced with a short "a" sound. The second part, "uloma," is pronounced with a long "u" sound. The third part, "sarcomatodes," is a combination of the words "sarcoma" and "todes," which are pronounced as they appear.
Granuloma sarcomatodes, also known as granuloma faciale and granuloma telangiectaticum, is a rare benign skin disorder characterized by the presence of firm, red or purple papules or nodules on the face. It is a type of granulomatous inflammation that primarily affects the dermis, although the exact cause of the condition is unknown.
The term "granuloma" refers to a small mass or nodule that forms in response to injury or inflammation. In the case of granuloma sarcomatodes, the granulomas are characterized by the presence of spindle-shaped cells, resembling those found in sarcoma, a malignant tumor of connective tissue. However, it is important to note that granuloma sarcomatodes is a benign condition, not a true sarcoma.
Clinically, granuloma sarcomatodes typically presents as solitary or multiple reddish-brown or violaceous papules or nodules that are usually painless. These lesions may be slightly raised, and in some cases, may develop a telangiectatic appearance due to the presence of dilated blood vessels. The condition primarily affects middle-aged to elderly individuals, with a slight predilection for males.
Diagnosis of granuloma sarcomatodes is usually made based on clinical appearance and confirmed by histopathological examination. A skin biopsy is performed to obtain a sample of the affected tissue, which is then analyzed under a microscope. The characteristic findings include a dense inflammatory infiltrate in the dermis, consisting of lymphocytes, histiocytes, and multinucleated giant cells.
Treatment options for granuloma sarcomatodes include topical or intralesional corticosteroids, cryotherapy, laser therapy, or surgical excision
Mycosis fungoides.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.