GRANULOMAS Meaning and
Definition
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Granulomas are defined as small nodules or masses of immune cells that form in various tissues in response to chronic inflammation or the presence of foreign substances. They are typically composed of specialized immune cells called macrophages, which are large white blood cells that play a key role in immune responses.
Granulomas are often seen in conditions such as tuberculosis, sarcoidosis, and certain fungal or parasitic infections. They can also occur as a result of exposure to certain materials, such as silica or beryllium, or as a response to foreign bodies, such as sutures or splinters.
These nodules form as a result of the body's attempt to contain and isolate foreign substances or chronic inflammation. The macrophages accumulate and surround the offending agent, forming a compact structure known as a granuloma. Other immune cells, such as T cells, may also be present within the granuloma, assisting in the immune response. However, despite the immune cells' efforts, the granuloma often persists as a chronic condition.
The presence of granulomas can cause damage to tissues, depending on their location and size. In some cases, granulomas may resolve on their own, especially with appropriate treatment for the underlying cause. However, in other cases, they may become fibrotic or calcified, leading to long-term tissue damage or scarring. Therefore, understanding the formation and characteristics of granulomas is crucial in diagnosing and managing various diseases and conditions.
Common Misspellings for GRANULOMAS
Etymology of GRANULOMAS
The word "granulomas" is derived from the Greek words "gránoulon" meaning "granule" or "small grain", and "-oma", which is a suffix used to describe a tumor or abnormal growth. In medical terminology, granulomas refer to small nodules or masses that form in response to various chronic inflammatory conditions, infections, or immune responses.
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