Granuloma inguinale tropicum, also known as donovanosis or granuloma venereum, is a chronic, sexually transmitted infection caused by the bacterium Klebsiella granulomatis. This condition primarily affects the genital area, but can also affect other regions of the body, including the perianal region and the mouth.
The disease typically begins with the appearance of painless, raised lesions or nodules on the affected areas. Over time, these nodules develop into ulcerative, destructive lesions that can erode the surrounding tissues. The infection spreads progressively and can lead to significant tissue damage if left untreated.
Granuloma inguinale tropicum is transmitted through sexual contact, including vaginal, anal, or oral sex, typically with an infected individual. It is more prevalent in tropical regions with poor sanitation and crowded living conditions, where it is more likely for transmission to occur.
The diagnosis of granuloma inguinale tropicum is made by identifying the characteristic appearance of the lesions and performing laboratory tests to confirm the presence of Klebsiella granulomatis bacteria. Treatment usually involves a prolonged course of antibiotics such as doxycycline, erythromycin, azithromycin, or ciprofloxacin. In advanced cases with extensive tissue destruction, surgical intervention may be necessary to manage complications and repair damaged areas.
Overall, granuloma inguinale tropicum is a chronic bacterial infection that primarily affects the genital area, characterized by painless nodules that progress to ulcerative lesions. Its diagnosis is confirmed through laboratory tests, and treatment typically involves antibiotics.
