How Do You Spell GLUTATHIONE TRANSFERASE E?

Pronunciation: [ɡlˌuːtɐθˈa͡ɪ͡əni tɹansfˈɜːɹe͡ɪz ˈiː] (IPA)

Glutathione Transferase E, a crucial enzyme involved in detoxification, is often misspelled due to its complex phonetic structure. The correct pronunciation is /ɡljuːtəθaɪəʊn trænsfəreɪs iː/. The first three syllables emphasize the gluteus muscle, followed by a combination of the soft "th" sound and an "aye" ending. The final syllables consist of the word "transfer" with an "-ase" suffix, followed by the letter "E." Ensuring proper spelling is crucial to avoid miscommunication in the scientific community where this enzyme is studied and utilized.

GLUTATHIONE TRANSFERASE E Meaning and Definition

1. Glutathione Transferase E (GST-E) is a class of enzymes that play a crucial role in the cellular defense system, particularly in the detoxification process. These enzymes belong to a larger family of glutathione transferases (GSTs) and are involved in the conjugation of glutathione (a tripeptide molecule composed of cysteine, glycine, and glutamate) with various hydrophobic electrophiles. The primary function of GST-E is to catalyze the transfer of the glutathione moiety to a wide range of endogenous and exogenous substrates, including toxins, carcinogens, and reactive oxygen species.

   GST-E acts as a phase II detoxification enzyme, participating in the biotransformation process that converts lipophilic compounds into more water-soluble forms, facilitating their excretion from the body. By conjugating glutathione to these potentially harmful chemical compounds, GST-E assists in rendering them less toxic and more easily eliminated via urine or bile.

   Beyond its detoxification role, GST-E also contributes to the regulation of oxidative stress and cell signaling pathways. It is involved in protecting cells from damage caused by reactive oxygen and nitrogen species, which can lead to DNA damage, oxidative stress, and cell death.

   Overall, GST-E is an essential enzyme that helps maintain cellular homeostasis by metabolizing and eliminating toxic compounds from the body, protecting against oxidative damage, and regulating signal transduction pathways.

Common Misspellings for GLUTATHIONE TRANSFERASE E

• flutathione transferase e
• vlutathione transferase e
• blutathione transferase e
• hlutathione transferase e
• ylutathione transferase e
• tlutathione transferase e
• gkutathione transferase e
• gputathione transferase e
• goutathione transferase e
• glytathione transferase e
• glhtathione transferase e
• gljtathione transferase e
• glitathione transferase e
• gl8tathione transferase e
• gl7tathione transferase e
• glurathione transferase e
• glufathione transferase e
• glugathione transferase e
• gluyathione transferase e
• glu6athione transferase e