How Do You Spell GLUCOSE CLAMP TECHNIC?

Pronunciation: [ɡlˈuːkə͡ʊs klˈamp tˈɛknɪk] (IPA)

The "Glucose Clamp Technic" is a technique used to maintain a constant level of blood glucose during experiments. The word "glucose" is spelled phonetically as [ˈɡluːkəs], with the stress on the first syllable, and pronounced as GLOO-kose. The word "clamp" is spelled phonetically as [klæmp], with the stress on the first syllable, and pronounced as klamp. The word "technic" is spelled phonetically as [ˈtek-nik], with the stress on the first syllable, and pronounced as TEK-nik. Together, the spelling of "Glucose Clamp Technic" follows standard English pronunciation rules.

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GLUCOSE CLAMP TECHNIC Meaning and Definition

  1. Glucose Clamp Technique, also known as the Euglycemic-Hyperinsulinemic Clamp Technique, is a widely-used method in medical and scientific research to measure insulin sensitivity and assess glucose metabolism in vivo. It involves maintaining a constant blood glucose concentration while insulin is infused into the bloodstream at a variable rate, thus "clamping" the glucose level.

    The clamp technique involves several steps: First, a glucose solution is infused intravenously to maintain the blood glucose concentration at a predetermined target level. The target level is typically set at a normal physiological range to avoid hyperglycemia or hypoglycemia. Secondly, insulin is simultaneously infused into the bloodstream at a variable rate, usually at a higher concentration than that found under normal physiological conditions. This infusion of insulin causes the body's tissues, particularly the liver, muscles, and adipose tissues, to take up and utilize glucose from the bloodstream more efficiently. The glucose infusion rate (GIR) required to maintain the constant blood glucose level is then measured. This GIR is an indicator of whole-body insulin sensitivity.

    The glucose clamp technique provides a reliable assessment of insulin sensitivity and helps to study how different physiological and pharmacological factors influence glucose metabolism. It is commonly used in clinical trials to evaluate the efficacy of anti-diabetic medications and therapies. Additionally, this technique is valuable in studying disorders related to glucose metabolism, such as insulin resistance, diabetes, and metabolic syndrome.

Common Misspellings for GLUCOSE CLAMP TECHNIC

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