GLUCOSE CLAMP Meaning and
Definition
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A glucose clamp is a technique used in medical research to measure and regulate blood glucose levels in order to study the metabolism and effects of insulin in the body. This method involves infusing insulin and glucose simultaneously into an individual while constantly monitoring blood sugar levels.
The procedure of a glucose clamp typically begins by placing an intravenous (IV) line to administer insulin and glucose into the bloodstream. The participant's blood glucose level is then measured using a continuous glucose monitoring device to establish a baseline value. Once the baseline is determined, insulin is infused at a specific rate to lower blood sugar levels.
To maintain a constant blood glucose concentration, additional glucose is infused intravenously in response to frequent blood sample measurements. This is done using a computerized algorithm that calculates the amount of glucose required to maintain the target glucose level set by the researchers.
The glucose clamp technique allows researchers to precisely control and manipulate blood sugar levels, simulating a "clamp" effect on glucose concentration. This method permits the investigation of different parameters, such as insulin sensitivity, metabolic responses, or the effects of various substances on glucose regulation.
The glucose clamp is an essential tool in diabetes research and provides valuable insights into glucose metabolism, insulin action, and the development of new treatments for diabetes.
Common Misspellings for GLUCOSE CLAMP
- flucose clamp
- vlucose clamp
- blucose clamp
- hlucose clamp
- ylucose clamp
- tlucose clamp
- gkucose clamp
- gpucose clamp
- goucose clamp
- glycose clamp
- glhcose clamp
- gljcose clamp
- glicose clamp
- gl8cose clamp
- gl7cose clamp
- gluxose clamp
- gluvose clamp
- glufose clamp
- gludose clamp
- glucise clamp
Etymology of GLUCOSE CLAMP
The etymology of the word "glucose clamp" can be understood by examining the origins of the individual terms.
1. Glucose: The term "glucose" originated from the Greek word "glukus", meaning "sweet". It was first used in 1838 by French chemist Jean Dumas when analyzing the sugar content of grapes. Glucose is a type of sugar and a primary source of energy for living organisms.
2. Clamp: The term "clamp" has a broader etymological background. It comes from the Old English word "clam", which means "to hold tightly" or "to grip". The word evolved and was also influenced by Middle Dutch and Old High German words with similar meanings.
When combined, "glucose clamp" refers to a technique used in medical research to maintain a constant and controlled level of glucose in the blood, allowing scientists to study glucose metabolism, insulin function, and related processes.
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