TUBERCULIN Meaning and
Definition
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Tuberculin is a substance derived from the bacteria that causes tuberculosis (Mycobacterium tuberculosis) and used as a diagnostic tool in tuberculosis testing. It is a protein derivative that is obtained from the growth of the bacteria in a laboratory setting. Tuberculin is created by purifying the secretions and cell products of the bacteria, such as proteins, lipids, and cell wall components.
Tuberculin is primarily used in a sensitive skin test called the tuberculin skin test (TST) or Mantoux test. In this test, a small amount of tuberculin is injected just beneath the skin, usually on the forearm. The person being tested must return after a predetermined period of time, typically 48 to 72 hours, so that the healthcare provider can examine the injection site for a specific reaction.
A positive reaction to the tuberculin skin test indicates exposure to or infection with Mycobacterium tuberculosis, but further testing is required to confirm the presence of active tuberculosis disease. In a positive reaction, the skin at the test site typically shows localized redness, swelling, and induration (hardening or thickening).
Tuberculin is considered a highly valuable tool in tuberculosis control programs as it aids in the detection of latent tuberculosis infection and helps identify individuals who may require further evaluation or treatment. It plays a crucial role in efforts to control and prevent the spread of tuberculosis worldwide.
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A preparation made from cultures of the tubercle bacillus, employed as a means of diagnosis and in the treatment, by active immunization, of tuberculosis.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for TUBERCULIN
Etymology of TUBERCULIN
The word "tuberculin" is derived from the term "tubercle", which refers to a small rounded swelling or nodule. It comes from the Latin word "tuberculum", meaning a small tuber or swelling. The ending "-in" indicates a substance or product, commonly used in chemistry and medicine. "Tuberculin" specifically refers to a protein derivative derived from the tuberculosis bacteria, used in diagnostic skin tests for tuberculosis.
Similar spelling words for TUBERCULIN
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