PRECLINICAL TEST Meaning and
Definition
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A preclinical test refers to a scientific investigation conducted in the early stages of drug or product development before it is tested on humans. It is performed to assess the safety, effectiveness, and potential risks associated with a particular substance. This form of testing is typically conducted in laboratories or on animal models to determine the possible impact of a drug or therapeutic intervention on various biological systems.
During preclinical tests, scientists evaluate the pharmacological properties of a substance, including its absorption, distribution, metabolism, and excretion within living organisms. It also analyzes the drug's potential toxicity, side effects, and adverse reactions. Moreover, preclinical tests help researchers obtain essential data on the optimal dosage and route of administration for subsequent human trials.
Common preclinical testing techniques involve in vitro studies using isolated cells or tissues, as well as in vivo experiments using animal models. These tests aim to mimic the effects that a substance may have on human physiology and provide valuable insight into its potential therapeutic benefits. The findings from preclinical tests inform decisions on whether to proceed to human clinical trials or to modify and refine the compounds further before progressing.
Overall, preclinical tests play a crucial role in drug development, allowing scientists and researchers to gather vital information about a substance's safety profile and its possible efficacy. These tests are pivotal in identifying potential risks and ensuring that only the safest and most promising candidates progress to the next stages of evaluation.
Common Misspellings for PRECLINICAL TEST
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Etymology of PRECLINICAL TEST
The word "preclinical" is derived from two components: "pre-" and "clinical".
1. "Pre-" is a prefix that means "before" or "prior to". It is derived from the Latin word "prae", which has the same meaning.
2. "Clinical" originates from the Latin word "clinicus", which pertains to a bedridden patient. However, its modern usage refers to the practical aspect of medicine that involves direct patient care, diagnosis, and treatment.
When combined, "preclinical" refers to the phase before clinical trials where substances or interventions undergo testing in a laboratory or animal models, aiming to gather preliminary data on efficacy, safety, and dosage, prior to human trials.
Similar spelling words for PRECLINICAL TEST
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