PRECLINICAL PHASE Meaning and
Definition
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The preclinical phase refers to the initial stage of drug development or research, wherein comprehensive laboratory tests and experiments are conducted on various substances before they are assessed in human subjects. This phase is primarily aimed at evaluating the safety, tolerability, and effectiveness of potential drugs or therapies before they can progress to clinical trials involving human participants.
During the preclinical phase, scientists and researchers investigate the substance's pharmacokinetics (how the drug is absorbed, distributed, metabolized, and excreted by the body), pharmacodynamics (how the drug interacts with the body at the molecular level), and toxicity (any potential harmful effects on biological systems). This is typically done using in vitro studies (tests performed in test tubes or petri dishes) and in vivo studies (tests involving living organisms like mice or other animals).
Preclinical studies also play a crucial role in determining the appropriate dosage and route of administration for the drug under investigation. These experiments help researchers understand the substance's potential therapeutic benefits, potential risks or side effects, and any other relevant biological or physiological effects associated with its use.
The results obtained during the preclinical phase are vital in determining whether a drug or therapy progresses to the next stage of development, which typically involves clinical trials in humans. The purpose of conducting preclinical investigations is to gather substantial evidence supporting the safety, effectiveness, and potential benefits of the drug, ensuring its suitability for subsequent human testing.
Common Misspellings for PRECLINICAL PHASE
- oreclinical phase
- lreclinical phase
- -reclinical phase
- 0reclinical phase
- peeclinical phase
- pdeclinical phase
- pfeclinical phase
- pteclinical phase
- p5eclinical phase
- p4eclinical phase
- prwclinical phase
- prsclinical phase
- prdclinical phase
- prrclinical phase
- pr4clinical phase
- pr3clinical phase
- prexlinical phase
- prevlinical phase
- preflinical phase
Etymology of PRECLINICAL PHASE
The word "preclinical" is derived from the combination of the prefix "pre-" meaning "before" or "prior to" and the word "clinical" which relates to the observation and treatment of patients.
In the context of medical and pharmaceutical research, the term "preclinical phase" refers to the stage of testing and experimentation that precedes human clinical trials. During this phase, experiments are conducted in laboratories and on animals to assess the safety, efficacy, and potential side effects of potential treatments or drugs before they are tested on humans. The goal is to gather sufficient preclinical data to support the initiation of human trials.
Similar spelling words for PRECLINICAL PHASE
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