Neutrophilic Eccrine Hidradenitis (NEH) is a rare inflammatory skin disorder characterized by the formation of painful nodules or abscesses in the sweat glands called eccrine glands. This condition primarily affects middle-aged to elderly individuals, and it is associated with various underlying medical conditions such as infections, hematologic malignancies, and autoimmune diseases.
The term "neutrophilic" in NEH refers to the type of white blood cells involved in the inflammatory response. Neutrophils, a type of immune cell, accumulate in the affected sweat glands, leading to inflammation and subsequent formation of nodules or abscesses. These inflammatory lesions often present as red, swollen, and tender lumps in areas with a high concentration of sweat glands, such as the armpits, groin, or perianal region.
The symptoms of NEH may vary in severity, ranging from mild discomfort to severe pain. In some cases, the abscesses can burst, leading to the release of pus and potentially resulting in secondary bacterial infections. The diagnosis of NEH typically involves a thorough examination of the affected areas and may require a biopsy for confirmation.
Treatment for NEH aims to control the underlying condition contributing to the inflammation and manage the symptoms. This may involve treating infections or addressing any underlying autoimmune or hematologic disorders. Symptomatic relief can be achieved through warm compresses, pain medications, and antibiotics if bacterial infections are present.
Overall, Neutrophilic Eccrine Hidradenitis is a rare condition characterized by the formation of painful nodules or abscesses in sweat glands, typically associated with underlying medical conditions.
