IMMUNOHISTOCHEMISTRY Meaning and
Definition
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Immunohistochemistry is a laboratory technique in the field of pathology and histology that employs the use of specific antibodies to detect and locate specific proteins or antigens in tissue samples. It combines the principles of immunology and histology to visualize the distribution and expression of target molecules within cells and tissues.
In the process of immunohistochemistry, tissue sections are treated with antibodies that are labeled with a detectable marker, such as an enzyme or a fluorescent dye. These antibodies bind specifically to the target protein or antigen of interest within the tissue. The labeled antibodies allow for the visualization and localization of the target molecule under a microscope.
This technique is widely used in biomedical research and diagnostic pathology to study the expression patterns of various proteins in diseased and normal tissues. It helps researchers understand the molecular mechanisms involved in diseases and provides important information about the tissue characteristics and cellular components.
By using specific antibodies, such as monoclonal or polyclonal antibodies, immunohistochemistry enables researchers to identify and quantify the presence of proteins within cells or tissues, and to determine their localization and distribution patterns. This information is valuable in investigating the role of proteins in disease development, diagnosing specific diseases, and assessing the efficacy of potential targeted therapies.
In summary, immunohistochemistry is a powerful tool that combines immunology and histology to visualize and detect specific proteins or antigens in tissue samples, helping researchers and pathologists gain insights into disease processes and improve diagnostic accuracy.
Common Misspellings for IMMUNOHISTOCHEMISTRY
Etymology of IMMUNOHISTOCHEMISTRY
The word "immunohistochemistry" has its origins in three key components: immunology, histology, and chemistry.
The term "immunology" comes from the Latin word "immunis", meaning "exempt". It is defined as the branch of science that deals with the study of the immune system and immune responses.
"Histology" is derived from the Greek words "histos" meaning "tissue" and "logos" meaning "study" or "discourse". It refers to the study and microscopic examination of tissues and their cellular components.
The word "chemistry" is derived from the Arabic word "al-kīmiyā", which originally referred to the ancient practice of transmuting base metals into gold. It later evolved to encompass the study of chemical properties, composition, and interactions.
Similar spelling word for IMMUNOHISTOCHEMISTRY
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