IMMUNODOMINANT SITES Meaning and
Definition
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Immunodominant sites refer to specific regions or epitopes on an antigen molecule that have a strong affinity for the immune system and are recognized and targeted by antibodies or T-cells during an immune response. These sites play a crucial role in immunology as they are key determinants in the generation of an immune response against pathogens, vaccines, or allergens.
Immunodominant sites can be either linear or conformational. Linear immunodominant sites are continuous sequences of amino acids found in the primary structure of the antigen. On the other hand, conformational immunodominant sites are formed when non-contiguous amino acids come together in the folded, three-dimensional structure of the antigen.
The recognition and binding of immunodominant sites by immune cells, such as B-cells or T-cells, lead to the activation of an immune response. This can involve the production of antibodies that bind to the immunodominant epitopes on the antigen surface, blocking their activity or facilitating their elimination by other immune cells. Alternatively, T-cells can directly recognize immunodominant sites presented by antigen-presenting cells, triggering an immune response that helps in eliminating infected cells or pathogens.
Understanding immunodominant sites and their interactions with the immune system is essential for designing effective vaccines, diagnostic tests, and immunotherapies. Determining the immunodominant regions of an antigen can aid in predicting and enhancing the immune response, as well as identifying potential targets for therapeutic interventions.
Common Misspellings for IMMUNODOMINANT SITES
- ummunodominant sites
- jmmunodominant sites
- kmmunodominant sites
- ommunodominant sites
- 9mmunodominant sites
- 8mmunodominant sites
- inmunodominant sites
- ikmunodominant sites
- ijmunodominant sites
- imnunodominant sites
- imkunodominant sites
- imjunodominant sites
- immynodominant sites
- immhnodominant sites
- immjnodominant sites
- imminodominant sites
- imm8nodominant sites
- imm7nodominant sites
- immubodominant sites
- immumodominant sites
Etymology of IMMUNODOMINANT SITES
The word "immunodominant" is derived from the combination of two words: "immuno" and "dominant". "Immuno" comes from the Latin word "immunis", meaning "exempt" or "protected". "Dominant" originates from the Latin word "dominans", which means "ruling" or "prevailing".
The term "immunodominant" is used to describe specific regions or sites on antigens that elicit a strong immune response. These sites dominate or prevail in the immune response and are recognized and targeted by the immune system.
The word "sites" refers to the specific locations or areas on an antigen where the immune response is triggered. In the case of "immunodominant sites", these are the regions of an antigen that stand out as being particularly immunogenic or capable of inducing a robust immune response.
