Hexamethonium Dichloride Dihydrate is a chemical compound that is primarily used as a ganglionic blocker. It can be classified as a quaternary ammonium compound and functions as a nicotinic acetylcholine receptor antagonist. Its molecular formula is C12H30Cl2N2O2, indicating that it consists of twelve carbon atoms, thirty hydrogen atoms, two chlorine atoms, two nitrogen atoms, and two oxygen atoms.
When in the form of a dihydrate, it contains two molecules of water per molecule of the compound. This crystalline substance has a white or off-white color and is highly soluble in water, but relatively insoluble in organic solvents.
Hexamethonium Dichloride Dihydrate works by blocking the ganglionic receptors of the autonomic nervous system. By doing so, it prevents the transmission of nerve impulses between neurons, specifically affecting the parasympathetic nervous system. This compound is commonly used in experimental and research settings to investigate the function of the autonomic nervous system and to study neural pathways.
Due to its mechanism of action, Hexamethonium Dichloride Dihydrate has various medical applications. It has been used to treat and manage high blood pressure, specifically in cases where other antihypertensive medications have not been effective. Additionally, it has been utilized in experimental treatments for different types of neuropathic pain and as an anesthesia adjuvant to reduce blood pressure during surgeries.
It is important to note that Hexamethonium Dichloride Dihydrate should only be used under strict medical supervision and in accordance with the prescribed dosage, as its misuse or administration by untrained individuals can lead to severe side effects or complications.
