HEXAMETHONIUM BROMIDE Meaning and
Definition
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Hexamethonium bromide is a chemical compound that is categorized as a quaternary ammonium antihypertensive drug, primarily used as a ganglionic blocker. It is a crystalline powder with a white to yellowish appearance and has a molecular formula of C13H26BrN. Hexamethonium bromide is known for its ability to selectively block nicotinic acetylcholine receptors in the autonomic ganglia, leading to the inhibition of both sympathetic and parasympathetic outflows. As a result, it acts as a non-depolarizing antagonist, effectively interrupting the transmission of nerve impulses between preganglionic and postganglionic neurons.
The pharmacological use of this compound revolves around its ability to lower blood pressure in cases of severe hypertensive emergencies. It achieves this by reducing sympathetic outflow, ultimately leading to vasodilation and decreased peripheral resistance. Hexamethonium bromide is not absorbed orally due to its quaternary ammonium structure, requiring administration through intravenous or intramuscular means. The effects of this agent last for a few hours, necessitating subsequent doses for prolonged therapeutic effect.
Aside from its medical applications, hexamethonium bromide has also been utilized as an experimental tool in physiological and pharmacological research. Due to its specific antagonistic action on nicotinic acetylcholine receptors, it has been instrumental in studying the role of autonomic ganglia in various bodily functions, such as regulation of blood pressure, heart rate, and gastrointestinal motility.
Common Misspellings for HEXAMETHONIUM BROMIDE
- gexamethonium bromide
- bexamethonium bromide
- nexamethonium bromide
- jexamethonium bromide
- uexamethonium bromide
- yexamethonium bromide
- hwxamethonium bromide
- hsxamethonium bromide
- hdxamethonium bromide
- hrxamethonium bromide
- h4xamethonium bromide
- h3xamethonium bromide
- hezamethonium bromide
- hecamethonium bromide
- hedamethonium bromide
- hesamethonium bromide
- hexzmethonium bromide
- hexsmethonium bromide
- hexwmethonium bromide
- hexqmethonium bromide
Etymology of HEXAMETHONIUM BROMIDE
The word "Hexamethonium Bromide" is a chemical compound name and not an everyday word, therefore it does not have a conventional etymology like regular words do. However, breaking down the term can shed some light on its origin:
1. Hexa: The prefix "hexa-" is derived from the Greek word "hex", meaning six. In chemical terms, it indicates the presence of six atoms of a particular element or a six-membered ring structure.
2. Methonium: This part of the word comes from the compound "methonium ion", which refers to a positively charged molecule containing a central carbon atom connected to three methyl (CH3) groups and one organic group. The term "methonium" is derived from methyl, meaning it is related to the presence of methyl groups in the compound.
