How Do You Spell GLUTAMATE CARBOXY LYASE?

Pronunciation: [ɡlˈuːtɐmˌe͡ɪt kˈɑːbɒksi lˈa͡ɪe͡ɪs] (IPA)

Glutamate carboxy lyase is a complex scientific term used in biochemistry. It is spelled as /ɡlu:təmeɪt kɑ:bɒksi 'laɪeɪs/. This term denotes an enzyme that helps in the biosynthesis of the amino acid cysteine in plants and bacteria. The word is constructed from the roots "glutamate", "carboxy", and "lyase". Each of these roots has a distinct meaning that contributes to the full meaning of the term. Understanding IPA phonetic transcription helps people to precisely articulate and comprehend the word.

GLUTAMATE CARBOXY LYASE Meaning and Definition

1. Glutamate Carboxy Lyase (GLC) is an enzyme that plays a crucial role in the metabolism of glutamate, a non-essential amino acid. It catalyzes the reversible decarboxylation of L-glutamate to form γ-aminobutyric acid (GABA) and carbon dioxide. This reaction is the first and rate-limiting step in the GABA shunt pathway.

   GLC is primarily found in certain bacteria, such as Escherichia coli, where it is encoded by the gadB gene. It is also present in some plants and mammals, albeit with different functions. In bacteria, GLC is part of the glutamate-dependent acid resistance system, which helps these organisms survive in acidic environments by converting excess glutamate into GABA, reducing intracellular pH. In plants, GLC has been implicated in seed dormancy and germination, as well as in stress responses.

   The enzymatic activity of GLC involves the binding of glutamate to the active site of the enzyme, followed by the release of the carboxyl group, resulting in the formation of GABA. GLC utilizes pyridoxal phosphate (PLP) as a cofactor, which participates in the decarboxylation process by forming a Schiff base with the amino acid substrate.

   The study of GLC and its regulation is of great interest in various fields, including biochemistry, microbiology, and plant biology, as it provides insights into the roles of GABA and glutamate metabolism in different organisms.

Common Misspellings for GLUTAMATE CARBOXY LYASE

• flutamate carboxy lyase
• vlutamate carboxy lyase
• blutamate carboxy lyase
• hlutamate carboxy lyase
• ylutamate carboxy lyase
• tlutamate carboxy lyase
• gkutamate carboxy lyase
• gputamate carboxy lyase
• goutamate carboxy lyase
• glytamate carboxy lyase
• glhtamate carboxy lyase
• gljtamate carboxy lyase
• glitamate carboxy lyase
• gl8tamate carboxy lyase
• gl7tamate carboxy lyase
• gluramate carboxy lyase
• glufamate carboxy lyase
• glugamate carboxy lyase
• gluyamate carboxy lyase
• glu6amate carboxy lyase