Chronic Progressive Paraparesis (CPP) is a medical condition that is characterized by a progressive weakness and loss of coordination in the lower extremities, leading to difficulty in walking and maintaining balance. The term "chronic" refers to the long-term, often lifelong nature of the condition, while "progressive" indicates that the symptoms typically worsen over time. "Paraparesis" specifically refers to weakness and partial paralysis affecting both legs.
CPP is commonly associated with degenerative neurological disorders that affect the spinal cord, such as multiple sclerosis, spinal cord tumors, or certain genetic conditions. It can also result from infections, such as the Human T-cell Lymphotropic Virus Type I (HTLV-I) which causes HTLV-associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).
The main symptoms of CPP include a gradual onset of muscle weakness and stiffness in the legs, with difficulties in walking, running, or climbing stairs. Over time, individuals with CPP may experience muscle wasting, loss of sensation, and bowel/bladder impairments. The severity and progression of symptoms can vary widely among affected individuals.
Diagnosis of CPP typically involves a thorough medical history, physical examination, and various imaging tests to evaluate the condition of the spinal cord. Treatment options mainly focus on managing symptoms and may include physical therapy, assistive devices (e.g., canes or braces), medications to alleviate pain or manage underlying causes, and in some cases, surgery.
In conclusion, Chronic Progressive Paraparesis is a chronic and progressive condition characterized by the gradual weakening and coordination difficulties in the lower extremities. It is associated with various disorders affecting the spinal cord, leading to difficulties in walking and maintaining balance.
