How Do You Spell CARBONYL REDUCTASES?

Pronunciation: [kˈɑːbənˌa͡ɪl ɹɪdˈʌkte͡ɪsɪz] (IPA)

Carbonyl reductases are a group of enzymes that play an important role in drug metabolism and synthesis. The pronunciation of this word can be broken down into individual sounds using the International Phonetic Alphabet (IPA). The first syllable, "car," is pronounced /kɑːr/. The second syllable, "bo," is pronounced /bɒ/. The third syllable, "nyl," is pronounced /naɪl/. Finally, "reductases" is pronounced /rɪˈdʌktəsez/. By breaking down the word using IPA, one can more easily understand its spelling and pronunciation.

CARBONYL REDUCTASES Meaning and Definition

1. Carbonyl reductases are a group of enzymes that facilitate the reduction of carbonyl compounds, which are molecules containing a carbon-oxygen double bond (C=O). Carbonyl reductases are present in various organisms, including bacteria, fungi, plants, and animals, including humans.

   These enzymes play a crucial role in the metabolism of carbonyl compounds by catalyzing the NADPH-dependent reduction reaction. NADPH (nicotinamide adenine dinucleotide phosphate) is an essential cofactor that provides the necessary reducing power for the reaction. Carbonyl reductases can specifically bind to carbonyl compounds and transfer a hydride ion (H-) from NADPH to the carbonyl carbon atom, converting the double bond into a single bond. This reduction reaction leads to the formation of a corresponding alcohol.

   The substrate specificity of carbonyl reductases can vary, meaning different enzymes may have different preferences for the carbonyl compounds they act upon. For instance, some carbonyl reductases are specialized in reducing aldehydes, while others are more effective in reducing ketones.

   The activity of carbonyl reductases is involved in various biological processes, including the detoxification of harmful chemicals and drugs, cellular defense against oxidative stress, and biosynthesis of important metabolites. In addition, these enzymes are also important targets for drug development, as they play a role in the metabolism of many drugs, affecting their efficacy, toxicity, and elimination from the body.

   Overall, carbonyl reductases are critical enzymes involved in the reduction of carbonyl compounds, playing significant roles in both normal physiological processes and drug metabolism.

Common Misspellings for CARBONYL REDUCTASES

• xarbonyl reductases
• varbonyl reductases
• farbonyl reductases
• darbonyl reductases
• czrbonyl reductases
• csrbonyl reductases
• cwrbonyl reductases
• cqrbonyl reductases
• caebonyl reductases
• cadbonyl reductases
• cafbonyl reductases
• catbonyl reductases
• ca5bonyl reductases
• ca4bonyl reductases
• carvonyl reductases
• carnonyl reductases
• carhonyl reductases
• cargonyl reductases
• carbinyl reductases
• carbknyl reductases

Etymology of CARBONYL REDUCTASES

The word "carbonyl reductases" is composed of two main components: "carbonyl" and "reductases".

1. Carbonyl: The term "carbonyl" refers to a functional group in organic chemistry consisting of a carbon atom double-bonded to an oxygen atom (C=O). The term originates from the combination of "carbon" and "keto", representing a compound containing a carbon-oxygen double bond.

2. Reductases: The term "reductases" indicates a class of enzymes involved in reduction reactions. The suffix "-ase" denotes an enzyme, while "reduct" comes from the verb "reduce", meaning to decrease or chemically convert a compound by gaining electrons.

Therefore, "carbonyl reductases" refers to a group of enzymes that catalyze the reduction of carbonyl compounds.