Correct spelling for the English word "Amyline" is [ˈamɪlˌa͡ɪn], [ˈamɪlˌaɪn], [ˈa_m_ɪ_l_ˌaɪ_n] (IPA phonetic alphabet).
Amyline is a polypeptide hormone that is primarily secreted by the pancreas in response to high blood glucose levels. It plays a crucial role in the regulation of glucose metabolism and helps to maintain normal blood sugar levels. Amyline functions to slow down gastric emptying, which allows for a more gradual and controlled release of glucose into the bloodstream after a meal.
Amyline, also known as islet amyloid polypeptide (IAPP), is synthesized and co-secreted along with insulin from the beta cells of the pancreas. It acts as a secondary hormone to complement the effects of insulin in regulating glucose homeostasis. By slowing down the emptying process of the stomach, it helps to prevent spikes in blood sugar levels after a meal.
This hormone also plays a role in appetite regulation and satiety. It acts in conjunction with other hormones, such as leptin and ghrelin, to provide feedback to the brain about energy intake and storage. Amyline contributes to the feeling of fullness and assists in controlling the amount of food consumed.
In certain individuals with type 2 diabetes, amyline production may be impaired, leading to reduced secretion and abnormal accumulation, resulting in the formation of amyloid plaques in the pancreas. This can contribute to the progression of the disease and may further impair glucose regulation.
Overall, amyline is an essential hormone involved in glucose metabolism, gastric emptying, appetite regulation, and maintaining stable blood sugar levels, making it a crucial component of overall metabolic health.
The insoluble part of starch.
Etymological and pronouncing dictionary of the English language. By Stormonth, James, Phelp, P. H. Published 1874.