THROMBIN TIME Meaning and
Definition
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Thrombin Time is a medical term used to describe a laboratory test that measures the time it takes for blood to clot. Specifically, it assesses the final step in the coagulation cascade, which is the conversion of fibrinogen to fibrin by the enzyme thrombin. The test is typically conducted when there is suspicion of a bleeding disorder or to monitor patients receiving anticoagulant therapy.
To perform the Thrombin Time test, a clinician would add a standardized amount of thrombin to a blood sample, which triggers the clotting process. The clinician then measures the time it takes for the blood sample to form a fibrin clot. This duration is compared to a reference range, which is typically around 10-14 seconds in healthy individuals.
A prolonged Thrombin Time may indicate a deficiency or dysfunction in one or more coagulation factors involved in the conversion of fibrinogen to fibrin. It can be caused by conditions such as liver disease, disseminated intravascular coagulation, or genetic deficiencies in fibrinogen or other coagulation factors. Additionally, certain medications, such as anticoagulants, may prolong the Thrombin Time.
Conversely, a decreased Thrombin Time may suggest the presence of a hypercoagulable state, where the blood has a heightened tendency to form clots. This can occur in conditions like deep vein thrombosis, pulmonary embolism, or thrombophilia.
Overall, Thrombin Time is an important laboratory test that aids in the diagnosis and management of bleeding and clotting disorders by assessing the functionality of the final step in the blood coagulation process.
Common Misspellings for THROMBIN TIME
- rhrombin time
- fhrombin time
- ghrombin time
- yhrombin time
- 6hrombin time
- 5hrombin time
- tgrombin time
- tbrombin time
- tnrombin time
- tjrombin time
- turombin time
- tyrombin time
- theombin time
- thdombin time
- thfombin time
- thtombin time
- th5ombin time
- th4ombin time
- thrimbin time
- thrkmbin time
Etymology of THROMBIN TIME
The word "thrombin" comes from the Greek word "thrombos", which means "clot". "Time", in this context, refers to the period it takes for a specific event to occur. Therefore, the term "thrombin time" is used to describe the period it takes for a clot to form in a patient's blood when thrombin (a protein involved in blood clotting) is added.
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