THROMBIN Meaning and
Definition
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Thrombin is a noun that refers to a specialized enzyme found in blood plasma and platelets. It plays a crucial role in the process of clot formation and blood coagulation, which is important for preventing excessive bleeding after injury or trauma.
The production of thrombin occurs as a result of the activation of prothrombin, which is a precursor protein synthesized in the liver. Prothrombin is converted into its active form, thrombin, through a series of sequential enzymatic reactions known as the coagulation cascade. Thrombin then serves as a catalyst for the conversion of fibrinogen, another soluble plasma protein, into insoluble strands of fibrin. These strands intertwine to form a mesh-like structure that captures blood cells and platelets, resulting in the formation of a blood clot.
Furthermore, thrombin also plays a regulatory role in the coagulation process by acting on various factors involved in the cascade, amplifying the clotting response. Additionally, thrombin can activate platelets, leading to their aggregation and the release of factors that contribute to the formation and stabilization of blood clots.
Medical interventions have been developed to control the activity of thrombin, as hypercoagulability or exaggerated clot formation can lead to severe health conditions like deep vein thrombosis, stroke, or heart attack. On the other hand, inhibiting thrombin activity is important during surgical procedures to prevent clot formation and maintain blood flow.
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A ferment (the activated thrombogen) formed in the blood, after this is shed, which converts fibrinogen into fibrin; it is formed from the conjunction of prothrombin and calcium salts.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for THROMBIN
- rhrombin
- fhrombin
- ghrombin
- yhrombin
- 6hrombin
- 5hrombin
- tgrombin
- tbrombin
- tnrombin
- tjrombin
- turombin
- tyrombin
- theombin
- thdombin
- thfombin
- thtombin
- th5ombin
- th4ombin
- thrimbin
- tuhrombin
Etymology of THROMBIN
The word "thrombin" is derived from the Greek word "thrombos", meaning "clot" or "lump". The "-in" suffix in "thrombin" indicates that it is an enzyme. Therefore, "thrombin" refers to the enzyme responsible for the formation of blood clots.
Similar spelling words for THROMBIN
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