The spelling of the word "spirophore" can be confusing because of its roots in Greek. In IPA phonetic transcription, it is pronounced /spaɪrəfɔːr/. The "spiro" part comes from the Greek word "σπείρω" which means "to twist", and the "phore" part comes from the Greek word "φορέω" which means "to carry". Therefore, "spirophore" means a structure that carries a twisted or coiled appendage. This biological term is often used to describe the coiled structure on the body of certain fungi.
Spirophore is a term with origins in chemistry and refers to a structural feature exhibited by certain organic compounds. It describes a cyclic system within a molecule that contains a central atom, often carbon, surrounded by two or more groups that are bonded to it. These groups, known as "arms," extend outward from the central atom in a spiral-like arrangement, giving rise to the term "spirophore."
The spirophoric arrangement frequently results in compounds with unique stereochemistry, as the spatial arrangement of the arms can influence the molecule's properties and reactivity. This spatial arrangement can be essential for the compound's biological activity and allows it to interact with specific molecular targets in various pharmacological applications.
Furthermore, spirophores can be found in a diverse range of substances, including natural products, pharmaceuticals, and synthetic organic molecules. They are often associated with the presence of multiple rings within a molecule and contribute to the structural complexity of these compounds.
Spirophores have gained significant attention in the field of drug discovery and development due to their potential to exhibit enhanced biological activity and improved drug-like properties. Additionally, they offer an avenue for the synthesis of novel chemical entities with intricate structures and diverse functionalities.
In summary, a spirophore is a cyclic system within an organic compound that contains a central atom with two or more groups extending outward in a spiral-like arrangement. This structural feature impacts the compound's properties and reactivity, and it is commonly found in natural products and pharmaceuticals.
A sort of pneumatic cabinet used for artificial respiration; the patient is placed in the cabinet, with his head outside and as the air within is alternately exhausted and under pressure the patient is made to inhale and exhale.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
The word spirophore is derived from two Greek roots: spiro meaning to breathe or to coil and phore meaning bearer or carrier.