How Do You Spell SPIRONOLACTONE?

Pronunciation: [spˈa͡ɪ͡ənəlˌaktə͡ʊn] (IPA)

The medication "spironolactone" is often prescribed for conditions such as high blood pressure and hormonal acne. Its spelling may appear difficult at first glance, but it can be broken down using IPA phonetic transcription. The word begins with the consonant cluster /sp/, followed by the vowel sound /aɪ/ represented by the letter "i". The middle section of the word contains the consonants /r/ and /n/, which are separated by the vowel sound /oʊ/ represented by the letter combination "o". Finally, the word ends with the consonant cluster /l/ and /t/ followed by the vowel sound /oʊ/ represented by the letter "e".

SPIRONOLACTONE Meaning and Definition

1. Spironolactone is a medication primarily used as a diuretic, meaning it helps increase the production and excretion of urine, thereby promoting fluid losses from the body. It works by blocking the action of the hormone aldosterone in the kidneys. Aldosterone plays a crucial role in regulating the balance of water and sodium in the body. By inhibiting aldosterone's effects, spironolactone helps reduce the reabsorption of sodium and the excretion of potassium, leading to increased urine production.

   Apart from its diuretic effects, spironolactone also possesses antiandrogenic properties, meaning it can reduce the effects of androgens (male sex hormones) in the body. This is particularly useful in the treatment of certain hormonal conditions such as polycystic ovary syndrome (PCOS) or hirsutism, where excessive hair growth occurs due to androgen excess.

   Spironolactone is available in both brand and generic formulations and can be taken orally as a tablet or capsule. It is primarily prescribed by doctors for conditions like edema (fluid retention), hypertension (high blood pressure), heart failure, and primary aldosteronism. Additionally, it is sometimes used off-label for the treatment of acne vulgaris in women, as it can help reduce the production of sebum, the oily substance that contributes to acne formation.

   It's worth mentioning that spironolactone can interact with certain medications, so it is important to consult a healthcare professional before starting or stopping this medication. Additionally, individuals taking spironolactone may need regular monitoring of kidney function, electrolyte levels, and blood pressure to ensure optimal response and safety.

Common Misspellings for SPIRONOLACTONE

• apironolactone
• zpironolactone
• xpironolactone
• dpironolactone
• epironolactone
• wpironolactone
• soironolactone
• slironolactone
• s-ironolactone
• s0ironolactone
• spuronolactone
• spjronolactone
• spkronolactone
• sp9ronolactone
• sp8ronolactone
• spieonolactone
• spidonolactone
• spifonolactone
• spitonolactone

Etymology of SPIRONOLACTONE

The word "spironolactone" has its etymology rooted in the chemical structure and synthesis of the compound.

The term "spiro-" refers to the presence of a spiro ring system within the molecule. A spiro ring system consists of two rings that share a single atom, in this case, it is a sulfur atom (S).

The next part of the word, "-nol-", is derived from the compound's chemical structure. It is derived from the term "nol", which stands for "No OLeophilicity" or "No Lipophilicity" as spironolactone is a relatively non-lipophilic compound, meaning it has low affinity for fat or lipids.

Lastly, the suffix "-actone" signifies that spironolactone is a lactone compound.

Plural form of SPIRONOLACTONE is SPIRONOLACTONES