Retinal Anlage Tumor refers to a rare type of tumor that originates from the retinal anlage, which is a precursor structure of the developing retina. This tumor is typically identified during infancy or early childhood and is often categorized under the group of congenital retinal tumors.
Retinal anlage tumors are believed to arise from the mutation of certain genes responsible for normal eye development. The exact cause of these gene mutations is not well understood, and the occurrence of this tumor is considered sporadic, meaning it does not appear to be hereditary or genetically transmitted.
Clinically, retinal anlage tumors typically present as an intraocular mass that may lead to visual impairment or visual loss if not promptly treated. Signs and symptoms of this tumor may include leukocoria (a white pupil reflex), strabismus (crossed or misaligned eyes), and decreased visual acuity.
The diagnosis of retinal anlage tumor often involves a comprehensive ophthalmological examination, including indirect ophthalmoscopy, ultrasound, and imaging studies such as magnetic resonance imaging (MRI) or computed tomography (CT) scan. A histopathological examination of a biopsy sample may also be necessary to confirm the diagnosis.
Treatment options for retinal anlage tumor depend on factors such as the location, size, and aggressiveness of the tumor. The management may involve surgical removal of the tumor, laser therapy, cryotherapy (freezing treatment), chemotherapy, or a combination thereof. However, due to the rarity of this tumor, there is limited data available on the long-term outcomes and overall prognosis of affected individuals.
