RADIATION HYBRID Meaning and
Definition
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Radiation hybrid is a genetic mapping technique used to create a specialized type of cell line known as a radiation hybrid cell line. These cell lines are a result of fusing normal cells with cells that have been irradiated with high levels of radiation. The primary purpose of radiation hybrid mapping is to create a tool that allows researchers to precisely map the location of genes along chromosomes.
The process of creating a radiation hybrid cell line involves exposing normal cells to high doses of radiation, which causes the chromosomes within the cell to break. These cells are then carefully fused with other cells that are susceptible to fusion. The resulting hybrid cells possess a mixed collection of chromosomes, with some originating from the irradiated cells and others from the unfused cells.
Radiation hybrid cell lines are highly valuable for genome mapping because the frequency at which chromosomal breaks occur is directly proportional to the distance between genes. By analyzing the radiation hybrid cell lines, researchers can determine the likelihood of specific genes being located near each other on a chromosome.
This technique has proven to be particularly useful in mapping genetic markers and identifying the physical locations of disease-associated genes. Overall, radiation hybrid mapping provides an effective tool for elucidating genome structure and organization, contributing to advancements in fields such as genetics, genomics, and medicine.
Common Misspellings for RADIATION HYBRID
- eadiation hybrid
- dadiation hybrid
- fadiation hybrid
- tadiation hybrid
- 5adiation hybrid
- 4adiation hybrid
- rzdiation hybrid
- rsdiation hybrid
- rwdiation hybrid
- rqdiation hybrid
- rasiation hybrid
- raxiation hybrid
- raciation hybrid
- rafiation hybrid
- rariation hybrid
- raeiation hybrid
- raduation hybrid
- radjation hybrid
- radkation hybrid
- radoation hybrid
Etymology of RADIATION HYBRID
The word "radiation" comes from the Latin word "radiare", which means "to emit rays or radiate". It is derived from the Latin word "radius", meaning "ray or spoke". "Radiation" is the process by which energy is emitted as particles or electromagnetic waves, often associated with the release of energy from atomic nuclei.
The term "hybrid" refers to a combination or mixture of different elements or entities. It comes from the Latin word "hybridus", which means "of mixed origin". In biology, "hybrid" is used to describe a plant or animal resulting from a crossbreeding of different species or varieties.
Therefore, in the context of "Radiation Hybrid", the term refers to a technique used in genetic mapping and analysis. It involves inducing radiation damage to chromosomes and then fusing them with intact cells to create a hybrid cell line.
