Rachischisis is a medical term that refers to a rare birth defect where the spinal cord does not completely form during fetal development. The correct pronunciation of this word is rə-ˈki-sə-səs, with the initial "r" being pronounced as a voiced alveolar trill or flap, and the "ch" being pronounced as a voiceless palatal fricative. The second syllable is spelled with the letter "s" twice in order to indicate that both "s" sounds are pronounced separately, as opposed to being blended into a single sound.
Rachischisis is a medical term derived from Greek roots, where "rachi-" means "spine" and "-schisis" refers to a split or fissure. It is a rare and severe congenital birth defect characterized by an incomplete closure of the neural tube during early embryonic development. The neural tube is the precursor to the spinal cord and brain, and its failure to fuse properly causes an open defect in the spine.
In cases of rachischisis, the affected fetus or newborn manifests a complete failure of the posterior midline structures of the spine to form, resulting in a wide, exposed cleft or gap along the entire length of the spinal column. As a consequence, the delicate neural tissues of the spinal cord are left unprotected and exposed externally.
This condition is associated with significant neurological impairment and physical disabilities for the affected individual. Babies born with rachischisis commonly experience paralysis or weakness in the lower limbs, lack voluntary bowel and bladder control, and may also exhibit sensory deficits. Additional complications may arise, such as hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain) due to disruption in the normal flow of fluid.
Addressing rachischisis usually requires immediate surgical intervention to protect and cover the exposed spinal cord. Long-term management often involves a multidisciplinary approach, combining medical, surgical, physical, and occupational therapies. Although treatments can help alleviate symptoms and improve quality of life, the prognosis for individuals with rachischisis heavily depends on the severity and extent of the condition, with many individuals experiencing permanent disabilities.
The word "rachischisis" comes from two Greek roots: "rachis" and "schisis".
1. "Rachis" (ῥᾰχίς): It means "spine" or "back" in Greek. This term is derived from the Proto-Indo-European root "reh₁ḱ-", which meant "to walk" or "to move". Through various linguistic transformations, it evolved into the Greek word "rachis" referring to the backbone or spinal column.
2. "Schisis" (σχίσις): It means "a split" or "a division" in Greek. This word originated from the Proto-Indo-European root "*skhīd-", which meant "to split" or "to separate". Over time, this word transformed into the Greek term "schisis", which describes a splitting or division.