How Do You Spell POLYNUCLEOTIDE PHOSPHORYLASE?

Pronunciation: [pˌɒlɪnjˈuːklɪˌɒta͡ɪd fˈɒsfɔːɹˌɪle͡ɪs] (IPA)

The spelling of "Polynucleotide Phosphorylase" can be explained using IPA phonetic transcription. The word starts with /p/ and continues with /ɑlɪnjuːklɪətaɪd/. The stress falls on the third syllable /in/. Next, we have /fɒsfəraɪleɪs/, where again the stress falls on the third syllable /fə/. This enzyme is responsible for the synthesis and degradation of RNA in prokaryotic cells. With its complex spelling, it may seem intimidating, but it is a vital part of biological research.

POLYNUCLEOTIDE PHOSPHORYLASE Meaning and Definition

1. Polynucleotide phosphorylase is an enzymatic protein that plays a crucial role in various biological processes involving RNA molecules. It is an exoribonuclease, meaning it degrades RNA molecules by cleaving the phosphodiester bonds between nucleotides. Specifically, this enzyme catalyzes the removal of nucleotides from the 3' end of RNA molecules.

   In terms of structure, polynucleotide phosphorylase is a single-chain protein composed of two domains: an N-terminal catalytic domain and a C-terminal oligonucleotide/oligosaccharide-binding (OB) fold domain. The catalytic domain contains the active site responsible for the enzymatic activity, while the OB fold domain assists in binding RNA substrates.

   Polynucleotide phosphorylase has been found to be involved in multiple cellular processes, including mRNA decay, RNA maturation, and RNA surveillance. It is also involved in regulating the stability of various RNA molecules, such as ribosomal RNA, transfer RNA, and messenger RNA. Additionally, it has been implicated in the regulation of post-transcriptional gene expression and the control of RNA degradation rates.

   Overall, polynucleotide phosphorylase is a crucial enzyme in RNA metabolism, contributing to the maintenance of RNA homeostasis within cells. It acts as a key player in processes that require the controlled degradation of RNA molecules, aiding in the regulation of gene expression and the proper functioning of cellular mechanisms.

Common Misspellings for POLYNUCLEOTIDE PHOSPHORYLASE

• oolynucleotide phosphorylase
• lolynucleotide phosphorylase
• -olynucleotide phosphorylase
• 0olynucleotide phosphorylase
• pilynucleotide phosphorylase
• pklynucleotide phosphorylase
• pllynucleotide phosphorylase
• pplynucleotide phosphorylase
• p0lynucleotide phosphorylase
• p9lynucleotide phosphorylase
• pokynucleotide phosphorylase
• popynucleotide phosphorylase
• pooynucleotide phosphorylase
• poltnucleotide phosphorylase
• polgnucleotide phosphorylase
• polhnucleotide phosphorylase
• polunucleotide phosphorylase
• pol7nucleotide phosphorylase
• pol6nucleotide phosphorylase
• polybucleotide phosphorylase

Etymology of POLYNUCLEOTIDE PHOSPHORYLASE

The word "Polynucleotide Phosphorylase" is derived from several components:

1. Poly-: This prefix is derived from the Greek word "polus" meaning "many" or "much". In this case, it refers to the presence or formation of a large number of nucleotides in a molecule.

2. Nucleotide: This term comes from the Latin word "nucleus", which means "kernel" or "nucleus". It refers to the building blocks of nucleic acids (DNA and RNA) consisting of a sugar molecule, a phosphate group, and a nitrogenous base.

3. Phosphorylase: This word is derived from the term "phosphoryl" and the suffix "-ase". "Phosphoryl" refers to a chemical group consisting of a central phosphorus atom bonded to three oxygen atoms.