How Do You Spell PLASMA TRANSGLUTAMINASE?

Pronunciation: [plˈazmə tɹansɡlˈuːtɐmˌɪne͡ɪs] (IPA)

Plasma Transglutaminase is a term used in medical practice to diagnose conditions related to gluten intolerance. The spelling of this word can be explained using the International Phonetic Alphabet (IPA) transcription [plæzmə trænzɡluːtəmɪneɪs], which breaks down the pronunciation of each syllable. The first syllable, "plas-", represents the sound of "plæz," which is the same as the word "plaza." The second syllable, "-ma," is pronounced "mə." The word "Transglutaminase" has five syllables that are represented in IPA as [trænzɡluːtəmɪneɪs], with the "glu" and "ta" sounds pronounced separately.

PLASMA TRANSGLUTAMINASE Meaning and Definition

1. Plasma transglutaminase refers to an enzyme present in the blood called transglutaminase that plays a significant role in the diagnosis of celiac disease, an autoimmune disorder caused by the ingestion of gluten. Specifically, plasma transglutaminase is a subtype of transglutaminase known as tissue transglutaminase that is found in the plasma, or liquid component, of blood.

   In individuals with celiac disease, the immune system mistakenly responds to the presence of gluten, a protein commonly found in wheat, barley, and rye, by producing antibodies called immunoglobulin A (IgA). Plasma transglutaminase is directly involved in the formation of these IgA antibodies, known as anti-tissue transglutaminase antibodies (anti-tTG antibodies). The enzyme potentiates the creation of these antibodies by modifying gluten proteins, leading to the recognition and binding of these proteins by the immune system.

   The levels of plasma transglutaminase can be measured through a blood test to assess the presence or severity of celiac disease. Elevated levels of plasma transglutaminase (anti-tTG) antibodies can indicate the presence of gluten-induced damage to the digestive system, thus aiding in the diagnosis of celiac disease. Furthermore, monitoring plasma transglutaminase levels over time can serve as a useful tool to track the progression of the disease or evaluate the effectiveness of gluten-free diets or treatments.

   In summary, plasma transglutaminase refers to the tissue transglutaminase enzyme found in the plasma of blood, which is responsible for the production of anti-tissue transglutaminase antibodies. Its measurement is crucial in the diagnosis and management of celiac disease.

Common Misspellings for PLASMA TRANSGLUTAMINASE

• olasma transglutaminase
• llasma transglutaminase
• -lasma transglutaminase
• 0lasma transglutaminase
• pkasma transglutaminase
• ppasma transglutaminase
• poasma transglutaminase
• plzsma transglutaminase
• plssma transglutaminase
• plwsma transglutaminase
• plqsma transglutaminase
• plaama transglutaminase
• plazma transglutaminase
• plaxma transglutaminase
• pladma transglutaminase
• plaema transglutaminase
• plawma transglutaminase
• plasna transglutaminase
• plaska transglutaminase
• plasja transglutaminase

Etymology of PLASMA TRANSGLUTAMINASE

The word "plasma transglutaminase" is derived from two main components: "plasma" and "transglutaminase".

- Plasma: The term "plasma" is derived from the Ancient Greek word "plásma" (πλάσμα), which means "something molded or formed". In modern usage, "plasma" refers to the liquid component of blood that carries nutrients, hormones, and waste materials around the body. The term was first introduced in the late 18th century.

- Transglutaminase: "Transglutaminase" is a compound word composed of two parts: "trans-" and "glutaminase".

-- Trans-: The prefix "trans-" is derived from the Latin word "trans", meaning "across" or "beyond".