How Do You Spell PLASMA THROMBOPLASTIN COMPONENT?

Pronunciation: [plˈazmə θɹˈɒmbəplˌastɪn kəmpˈə͡ʊnənt] (IPA)

The term "Plasma Thromboplastin Component" refers to a protein in the blood that is essential for the clotting process. The spelling of this word can be explained using the International Phonetic Alphabet (IPA) as /ˈplæzmə ˈθrɒmbəˌplæstin ˈkɒmpənənt/. It is pronounced with stress on the first, third, and fifth syllables. The spelling of the word accurately represents the sounds made when pronouncing it, with each syllable being sounded out clearly. This term is commonly used in medical contexts, particularly in discussions surrounding blood clotting disorders.

PLASMA THROMBOPLASTIN COMPONENT Meaning and Definition

1. Plasma thromboplastin component refers to a protein complex involved in the coagulation (clotting) process of blood. It is an essential component of the intrinsic pathway, one of the two pathways in the coagulation cascade.

   The term "plasma thromboplastin component" often specifically refers to factor XI, which is also known as plasma thromboplastin antecedent (PTA). Factor XI is one of the clotting factors found in blood plasma that is crucial for plugging damaged blood vessels and preventing excessive bleeding. It is synthesized in the liver and circulates in an inactive form until it is needed.

   When an injury to a blood vessel occurs, factor XI is activated by other intrinsic pathway components, such as activated factor XII and high molecular weight kininogen. Once activated, factor XI plays a key role in the conversion of factor IX to its active form, factor IXa. This subsequently leads to the activation of factor X, and the formation of a blood clot.

   A deficiency or dysfunction of factor XI can result in a bleeding disorder called hemophilia C. Individuals with this condition may experience prolonged and excessive bleeding following injuries or surgeries.

   Overall, plasma thromboplastin component (factor XI) is a vital protein involved in the coagulation of blood, ensuring proper clotting and preventing excessive bleeding.

Common Misspellings for PLASMA THROMBOPLASTIN COMPONENT

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