Photosensitisation (fəʊtəʊˌsɛnsɪtaɪˈzeɪʃən) is the process by which a substance becomes sensitive to light, sometimes causing an allergic reaction or other harmful effects. The spelling of this word includes the prefix "photo-" meaning "light," and the suffix "-sensitisation" meaning "to make sensitive." The IPA transcription breaks down the word into individual sounds, including the long "o" sound in "photo," the short "i" sound in "sensiti," and the "zay-shun" ending in "-sation," creating a complex and phonetically challenging word.
Photosensitisation refers to a physiological response exhibited by certain organisms, particularly living tissues, when exposed to light or radiation. It is a condition characterized by an exaggerated skin reaction or sensitivity caused by the interaction between sunlight or artificial light and certain chemicals, drugs, or naturally occurring substances present in the body.
In animals, photosensitisation can occur due to the ingestion of particular plants, such as St John's wort or clover, which contain photodynamic substances known as photosensitizers. These substances, when metabolized, can accumulate in the skin and other body tissues, making them sensitive to sunlight. As a result, affected animals may develop severe skin inflammation, blisters, and even tissue damage upon exposure to light, resulting in discomfort, pain, and potential long-term complications.
Photosensitisation can also be induced as a side effect of certain medications, like certain antibiotics, diuretics, or nonsteroidal anti-inflammatory drugs (NSAIDs). In humans, this condition may manifest as an allergic reaction with symptoms such as rash, redness, and itching upon light exposure. The severity of the reaction can vary, with some individuals experiencing mild sensitivity, while others may develop more severe symptoms.
To prevent photosensitisation, it is important to avoid exposure to sunlight or artificial light sources when susceptible to photosensitizers. This can be achieved through protective clothing, sunscreen application, or by avoiding known triggers. Medical advice should be sought to determine the underlying cause of the photosensitisation and appropriate treatment options.
The word "photosensitisation" is derived from the combination of two roots: "photo-" and "sensitisation".
The root "photo-" is derived from the Greek word "phos" (meaning "light") and is commonly used to refer to light-related terms, such as photography, photon, or photosynthesis.
The root "-sensitisation" is derived from the Latin word "sensitivus", which means "capable of feeling". "-Sensitisation" is a noun form of the verb "sensitize", indicating the process of becoming sensitive or reactive to a particular factor.
Therefore, "photosensitisation" combines the two roots to describe a condition or process whereby an organism becomes sensitized or reactive to light.