PENICILLIN ACYLASE Meaning and
Definition
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Penicillin Acylase is an enzyme that plays a crucial role in the production and purification of penicillin. This enzyme, also known as penicillin amidase or penicillin V acylase, is responsible for the hydrolysis of the side chain of penicillin molecules.
Penicillin is a widely used antibiotic that is highly effective against various bacterial infections. However, during its biosynthesis or synthesis, penicillin molecules are produced with an attached side chain, which needs to be removed to obtain the pure form of penicillin. This is where penicillin acylase comes into play.
The enzyme catalyzes the specific cleavage of the side chain from the penicillin molecules, resulting in the formation of penicilloic acids and penicillin G. This hydrolysis reaction is crucial for the production of penicillin because the presence of the side chain can affect its stability and efficacy.
Penicillin acylase is commonly used in industrial processes for the synthesis and purification of penicillin. It has also shown potential in the pharmaceutical industry for the synthesis of penicillin derivatives with enhanced antibacterial activity.
Furthermore, penicillin acylase has attracted significant attention due to its potential applications in biotechnology and medicine beyond penicillin production. It has been studied for its ability to catalyze various other enzymatic reactions, making it a versatile tool for the production of various biologically active compounds.
In conclusion, penicillin acylase is an enzyme that plays a crucial role in the production and purification of penicillin by catalyzing the hydrolysis of the side chain of penicillin molecules.
Common Misspellings for PENICILLIN ACYLASE
- oenicillin acylase
- lenicillin acylase
- -enicillin acylase
- 0enicillin acylase
- pwnicillin acylase
- psnicillin acylase
- pdnicillin acylase
- prnicillin acylase
- p4nicillin acylase
- p3nicillin acylase
- pebicillin acylase
- pemicillin acylase
- pejicillin acylase
- pehicillin acylase
- penucillin acylase
- penjcillin acylase
- penkcillin acylase
- penocillin acylase
- pen9cillin acylase
- pen8cillin acylase
Etymology of PENICILLIN ACYLASE
The word "penicillin acylase" has its origins in the field of biochemistry and pharmaceutical science.
Etymology breakdown:
- "Penicillin" refers to a group of antibiotics that are derived from fungi of the Penicillium genus, first discovered by Scottish scientist Alexander Fleming in 1928. The word is a combination of "penicillum", the Latin word for a brush or a type of paintbrush, and the suffix "-in" meaning a substance or compound.
- "Acylase" is derived from the term "acyl" and the suffix "-ase". "Acyl" refers to a chemical group derived from carboxylic acids, which is often involved in the structure of many organic compounds. The suffix "-ase" is commonly used to indicate an enzyme, which is a protein molecule that catalyzes specific biochemical reactions.
