PDGF BETA RECEPTOR Meaning and
Definition
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PDGF beta receptor is a type of receptor protein found on the surface of cells that is specifically designed to bind to and interact with platelet-derived growth factor (PDGF) beta. PDGF beta is a signaling protein that functions in the regulation of cell growth, division, and maturation. The PDGF beta receptor is a member of the receptor tyrosine kinase (RTK) family, which means it is capable of activating intracellular signaling pathways upon PDGF beta binding.
The PDGF beta receptor consists of several distinct regions, including an extracellular ligand-binding domain, a transmembrane domain, and an intracellular tyrosine kinase domain. Upon ligand binding, the extracellular domain of the receptor undergoes a conformational change that activates the tyrosine kinase domain. This activation leads to the phosphorylation of specific tyrosine residues on the receptor itself, as well as on downstream signaling molecules.
The activation of the PDGF beta receptor initiates a cascade of intracellular signaling events that ultimately regulate cell behavior. These include processes such as cell proliferation, migration, and differentiation. Dysregulation of the PDGF beta receptor pathway has been implicated in various diseases, including cancer, fibrosis, and vascular disorders. Therefore, the PDGF beta receptor and its associated signaling pathway serve as potential targets for therapeutic intervention in these conditions.
Common Misspellings for PDGF BETA RECEPTOR
- odgf beta receptor
- ldgf beta receptor
- -dgf beta receptor
- 0dgf beta receptor
- psgf beta receptor
- pxgf beta receptor
- pcgf beta receptor
- pfgf beta receptor
- prgf beta receptor
- pegf beta receptor
- pdff beta receptor
- pdvf beta receptor
- pdbf beta receptor
- pdhf beta receptor
- pdyf beta receptor
- pdtf beta receptor
- pdgd beta receptor
- pdgc beta receptor
- pdgv beta receptor
- pdgg beta receptor
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