Obstructive liver cirrhosis, also known as biliary cirrhosis or cholestatic cirrhosis, is a type of liver disease characterized by the development of scar tissue within the liver due to long-term blockage or obstruction of the bile ducts. The liver is responsible for producing bile, a substance necessary for the digestion and absorption of fats. Bile is normally transported to the intestines through a network of bile ducts, but in obstructive liver cirrhosis, these ducts become narrowed or blocked, preventing the flow of bile.
This obstruction leads to the accumulation of bile within the liver, causing inflammation, damage to liver cells, and ultimately leading to the formation of scar tissue. As the scar tissue accumulates, it progressively replaces healthy liver tissue, impairing the liver's ability to function properly. As a result, vital functions such as detoxification, production of blood clotting factors, metabolism of nutrients, and regulation of cholesterol levels are disrupted.
Common causes of obstructive liver cirrhosis include gallstones, strictures or narrowings in the bile ducts, tumors, or inflammation of the bile ducts. Symptoms may vary but can include yellowing of the skin and eyes (jaundice), itchy skin, fatigue, abdominal pain or discomfort, easy bruising or bleeding, and fluid retention. If left untreated, obstructive liver cirrhosis can progress to liver failure, affecting overall health and potentially becoming life-threatening.
Treatment of obstructive liver cirrhosis often involves addressing the underlying cause of the obstruction, relieving the blockage, managing symptoms, and preventing further liver damage. In severe cases, a liver transplant may be necessary to restore normal liver function. Regular monitoring and follow-up care are essential to managing the condition and preserving liver health
