The spelling of the word "myelocoel" is quite interesting. The first part of the word "myelo-" comes from the Greek word for "marrow," as in spinal cord marrow. The next part "-coel" comes from the Greek word "koilos," meaning "hollow." Thus, "myelocoel" refers to a hollow space in the spinal cord where the spinal cord fluid resides. In IPA phonetic transcription, it is pronounced /maɪloʊsiːl/.
Myelocoel is a medical term referring to a congenital condition characterized by the formation of a cyst-like cavity or sac within the spinal cord. The term is often used in the context of developmental abnormalities in which a fluid-filled space appears in the spinal cord, resulting in an open defect in the spinal column. Typically, the myelocoel is lined with a thin layer of tissue and contains cerebrospinal fluid.
The condition is believed to arise during early embryonic development, occurring as a result of incomplete fusion of the neural tube. This incomplete fusion gives rise to a defect in the vertebral arches, allowing the spinal cord to herniate through the opening and form a cystic structure. Myelocoels can vary in size and location along the spinal cord, and may be associated with other spinal cord abnormalities such as spina bifida.
Clinically, myelocoels can present with a range of symptoms depending on the location and size of the cyst. These symptoms may include neurological deficits such as muscle weakness, difficulty with coordination, sensory abnormalities, and bladder or bowel dysfunction. Management of myelocoel typically involves surgical intervention to repair and close the defect, which often requires careful assessment and planning to minimize the risk of neurological complications.
In summary, a myelocoel is a congenital condition characterized by the development of a fluid-filled cyst within the spinal cord, resulting from incomplete fusion of the neural tube during embryonic development. It can lead to a variety of neurological symptoms and typically requires surgical intervention for treatment.
The word "myelocoel" is derived from two Greek roots: "myelo" (meaning marrow) and "koilos" (meaning cavity or hollow). Combined, these roots form the term "myelocoel", which refers to a cavity or space filled with or surrounded by marrow.