MONOKINES Meaning and
Definition
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Monokines are a class of signaling molecules and cytokines secreted by immune cells, primarily monocytes and macrophages. These small proteins play a crucial role in the immune response and immune regulation within the body. Monokines can be released by activated immune cells in response to various stimuli, including infection, inflammation, and injury.
Monokines are involved in numerous physiological processes, such as cell communication, immune cell proliferation and activation, and inflammation regulation. They work by binding to specific receptors on target cells, triggering a cascade of signaling events that lead to the desired immune response. Additionally, monokines can influence the movement and migration of immune cells to target sites, aiding in the eradication of pathogens or tissue repair.
Some well-known monokines include tumor necrosis factor-alpha (TNF-α), interleukin-1 (IL-1), interleukin-6 (IL-6), and interferons. Each monokine has its unique function, often with overlapping roles in the immune response. For instance, TNF-α plays a vital role in inflammation and cell death, while IL-1 and IL-6 are important in initiating immune responses and triggering the acute-phase response.
Understanding the functions and regulations of monokines is crucial in the field of immunology, as dysregulation of their levels or activity can lead to immune disorders and diseases. Scientists and researchers study monokines to identify potential therapeutic targets and develop treatments for various inflammatory and autoimmune diseases.
Common Misspellings for MONOKINES
- monocine
- nonokines
- konokines
- jonokines
- minokines
- mknokines
- mlnokines
- mpnokines
- m0nokines
- m9nokines
- mobokines
- momokines
- mojokines
- mohokines
- monikines
- monkkines
- monlkines
- monpkines
- mon0kines
- mon9kines
Etymology of MONOKINES
The word "monokines" is derived from two roots: "mono-" and "-kine".
1. "Mono-" comes from the Greek word "monos", meaning "one" or "single". This prefix is used in words related to singularity, unity, or individuality.
2. "-Kine" is derived from the Greek word "kinein", meaning "to move". It is a common suffix used in various scientific terms related to movement, motion, or dynamics.
In the context of immunology and biology, "monokines" refer to a subset of immune signaling molecules, cytokines, that are produced by and act upon monocytes, a specific type of white blood cell involved in the immune response. These monokines help to regulate and coordinate immune system functions.
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