Mice Pneumonia Viruses (MPV) refers to a group of highly contagious viral pathogens that primarily infect mice and cause pneumonia-like symptoms. MPV belongs to the family of Murine Pneumoviruses, which is further classified into two main serotypes: MPV-1 and MPV-2.
MPV-1 and MPV-2 are enveloped, single-stranded RNA viruses that primarily affect the respiratory system of mice. The viruses primarily target the epithelial cells lining the upper and lower respiratory tracts, leading to severe respiratory distress. Infected mice often exhibit symptoms such as sneezing, coughing, labored breathing, and nasal discharge.
Transmission of MPV generally occurs through direct contact with infected mice or by inhaling respiratory secretions contaminated with the virus. In laboratory settings or mouse colonies, the virus can spread rapidly through aerosolized droplets, contaminated bedding, or shared equipment.
MPV can have a significant impact on mouse colonies due to its ability to cause fatal pneumonia outbreaks. However, the severity of the disease may vary depending on factors such as the virulence of the viral strain, the age and immune status of the host, and environmental conditions.
Researchers and scientists often study MPV as a model for understanding respiratory infections and immune responses in both mice and humans. MPV infections can be diagnosed using various techniques, such as serological tests, polymerase chain reaction (PCR), and virus isolation from respiratory secretions.
It is essential for researchers, veterinarians, and laboratory animal caretakers to implement strict biosecurity measures to prevent the spread of MPV and effectively manage its impact on mouse colonies.
