How Do You Spell METHIONYL TRNA SYNTHETASE?

Pronunciation: [mˈɛθɪˌɒna͡ɪl tˈiː ˌɑːɹˌɛnˈe͡ɪ sˈɪnθɪtˌe͡ɪs] (IPA)

Methionyl tRNA Synthetase is a vital enzyme involved in protein synthesis. Its complicated spelling can be explained using the International Phonetic Alphabet (IPA). The first syllable, "me-thi-o-nyl," is pronounced /mɛˈθaɪənəl/ with a short "e" sound, followed by a stressed long "i" sound. The second syllable, "tRNA," is pronounced /tiːˌɑrˈɛn/. The final word, "Synthetase," is pronounced /sɪnˈθɛtɪz/ with a short "i" sound and a stressed "e" sound in the second syllable. Overall, the spelling of Methionyl tRNA Synthetase reflects the complex and precise nature of the enzyme's function in the body.

Meaning and Definition
Common Misspellings
Basic Check Advanced Check

METHIONYL TRNA SYNTHETASE Meaning and Definition

  1. Methionyl tRNA synthetase, also called metRS, is an enzyme classified as a ligase, specifically within the aminoacyl-tRNA synthetase family. Methionyl tRNA synthetase is responsible for the process of aminoacylation, which involves attaching the amino acid methionine to its corresponding transfer RNA (tRNA) molecule. This enzyme plays a crucial role in protein synthesis, as it ensures that the correct amino acid is incorporated into growing polypeptide chains during translation.

    The methionyl tRNA synthetase enzyme has a high specificity for its substrate, methionine, as well as its respective tRNA molecule. In a two-step reaction, methionyl tRNA synthetase first activates methionine by binding it to adenosine monophosphate (AMP), creating a high-energy methionyl-AMP intermediate. In the second step, the activated methionine is transferred from AMP to the specific tRNA molecule designated for methionine, resulting in the production of methionyl-tRNA.

    This process of aminoacylation is crucial for maintaining the fidelity and accuracy of protein synthesis, as methionyl tRNA synthetase ensures that only methionine is incorporated into the growing polypeptide chain in response to the appropriate codon on the messenger RNA (mRNA) template. Any inaccuracies or errors in the methionyl tRNA synthetase enzyme can lead to disruptions in protein synthesis, potentially leading to a variety of cellular dysfunctions. Due to its essential role in protein synthesis, methionyl tRNA synthetase is highly conserved across different organisms and serves as an important target for drug development against certain infections and diseases.

Common Misspellings for METHIONYL TRNA SYNTHETASE

  • nethionyl trna synthetase
  • kethionyl trna synthetase
  • jethionyl trna synthetase
  • mwthionyl trna synthetase
  • msthionyl trna synthetase
  • mdthionyl trna synthetase
  • mrthionyl trna synthetase
  • m4thionyl trna synthetase
  • m3thionyl trna synthetase
  • merhionyl trna synthetase
  • mefhionyl trna synthetase
  • meghionyl trna synthetase
  • meyhionyl trna synthetase
  • me6hionyl trna synthetase
  • me5hionyl trna synthetase
  • metgionyl trna synthetase
  • metbionyl trna synthetase
  • metnionyl trna synthetase
  • metjionyl trna synthetase
  • metuionyl trna synthetase