Keratosis Palmaris et Plantaris, commonly known as palmoplantar keratoderma, is a dermatological condition characterized by the thickening and hardening of the skin on the palms of the hands and soles of the feet. This condition is non-contagious and often inherited as an autosomal dominant trait.
The primary symptom of Keratosis Palmaris et Plantaris is the formation of yellowish or brownish patches on the palms and soles. These patches can gradually expand and form thick, rough, and scaly plaques that may cause discomfort, pain, and difficulty in performing everyday activities such as walking and gripping objects. In severe cases, the keratoderma may cause fissures, blisters, or ulcers, leading to increased vulnerability to infections.
The exact cause of Keratosis Palmaris et Plantaris is not fully understood, but it is believed to be related to genetic mutations that affect the formation, structure, or metabolism of keratin, a protein responsible for the integrity and strength of the skin. Additionally, certain factors such as excessive friction, pressure, or repetitive trauma to the palms and soles can exacerbate the symptoms.
Treatment options for this condition aim to manage the symptoms and improve the quality of life of individuals affected. Medical interventions may include the application of topical medications, keratolytic agents, or moisturizers to soften the skin and reduce the scaling and thickening. Additionally, regular exfoliation and gentle removal of dead skin layers may be recommended.
Overall, Keratosis Palmaris et Plantaris is a chronic and progressive skin disorder characterized by the abnormal thickening and hardening of the palms and soles, causing discomfort and potential functional impairment.
