Keratosis Nigricans is a skin condition characterized by dark, thick, velvety patches on the skin. The word "keratosis" is spelled [ˌkɛrəˈtoʊsɪs], which is pronounced as KE-rə-TOH-sis. It is derived from the Greek word "kerato" which means "horny." "Nigricans" is spelled [nɪˈɡrɪkənz], and pronounced as nih-GRUH-kuhns. This word is derived from the Latin word "niger" which means "black". People with diabetes or those with insulin resistance are more prone to suffering from keratosis nigricans, as are those who are overweight.
Keratosis Nigricans is a medical condition characterized by the presence of dark, thickened, and velvety patches of skin. These patches typically develop on and around body folds such as the back of the neck, armpits, groin, and under the breasts. The affected areas may appear brown, black, or grayish in color and have a rough, warty texture.
The condition is most commonly associated with obesity and insulin resistance, and it often tends to occur in individuals with type 2 diabetes or those at risk of developing it. However, it can also be seen in people who are not overweight or diabetic, often due to a genetic predisposition.
Keratosis Nigricans is caused by an overgrowth of skin cells and an abnormal increase in a pigment called melanin. This abnormality is often a result of elevated levels of insulin in the blood, leading to the stimulation of certain skin cells, particularly the keratinocytes. Other underlying conditions, such as hormonal disorders or certain medications like oral contraceptives, can also contribute to the development of this condition.
Although Keratosis Nigricans itself is harmless, it is usually considered a marker for an underlying health issue, especially when the patches appear suddenly or become extensive. Therefore, a proper diagnosis and management of the underlying cause is necessary. Treatment options typically involve addressing the related condition, such as weight loss, controlling diabetes or managing hormone levels. Cosmetic measures like topical retinoids or laser therapy may also be used to improve the appearance of the affected skin.
The word "keratosis nigricans" has its roots in Greek and Latin.
The term "keratosis" is derived from the Greek word "keras", meaning "horn" or "hard, horny tissue", and the suffix "-osis", which denotes a condition or a state. In medical terminology, "keratosis" refers to a condition characterized by the thickening or overgrowth of the outermost layer of the skin.
The word "nigricans" comes from the Latin adjective "nigricans", which means "black" or "darkening". It is derived from the Latin verb "nigrare", meaning "to make black". The term is used to describe the dark, velvety patches that are a characteristic feature of keratosis nigricans.