KAPPA BUNGAROTOXIN Meaning and
Definition
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Kappa Bungarotoxin is a potent neurotoxin that is derived from the venom of the Bungarus snake species, particularly Bungarus multicinctus. It belongs to a class of neurotoxins known as long-chain alpha-neurotoxins (also referred to as α-neurotoxins). Kappa Bungarotoxin is known to specifically target and bind to the receptor sites of a specific group of neurotransmitter receptors known as nicotinic acetylcholine receptors (nAChRs).
The toxin acts by competitively binding to muscle-type (α1,β1,γ,δ) nAChRs and neuronal-type (α7) nAChRs, inhibiting the normal function of these receptors. By doing so, kappa Bungarotoxin disrupts the transmission of signals between nerve cells, ultimately leading to paralysis and severe muscle weakness. Due to its high affinity for nAChRs, even a small amount of this neurotoxin can cause potentially lethal effects.
Kappa Bungarotoxin has been widely utilized in scientific research as a tool to study the function and structure of nicotinic acetylcholine receptors. Its specific receptor-binding properties have made it particularly useful in the investigation of muscle diseases, such as myasthenia gravis, as well as in the development of potential therapeutic compounds for various neurological disorders.
In conclusion, kappa Bungarotoxin is a potent neurotoxin derived from the venom of Bungarus snakes, capable of selectively binding to nicotinic acetylcholine receptors and disrupting their normal function. Its use in scientific research has provided valuable insights into the functioning of these receptors and their potential as therapeutic targets.
Common Misspellings for KAPPA BUNGAROTOXIN
- jappa bungarotoxin
- mappa bungarotoxin
- lappa bungarotoxin
- oappa bungarotoxin
- iappa bungarotoxin
- kzppa bungarotoxin
- ksppa bungarotoxin
- kwppa bungarotoxin
- kqppa bungarotoxin
- kaopa bungarotoxin
- kalpa bungarotoxin
- ka-pa bungarotoxin
- ka0pa bungarotoxin
- kapoa bungarotoxin
- kapla bungarotoxin
- kap-a bungarotoxin
- kap0a bungarotoxin
- kappz bungarotoxin
- kapps bungarotoxin
- kappw bungarotoxin
Etymology of KAPPA BUNGAROTOXIN
The etymology of the term "kappa Bungarotoxin" can be broken down as follows:
1. Kappa: In this context, "kappa" is a Greek letter (κ) used in the scientific naming system to distinguish different variants or subtypes of a specific compound. It is often used to denote different isoforms or subunits within a group of related molecules.
2. Bungarotoxin: "Bungarotoxin" is a compound derived from the venom of the Bungarus genus of snakes, specifically the many-banded krait (Bungarus multicinctus). It was first isolated and purified in the mid-20th century by scientist Edward K. Lee. Bungarotoxin is a neurotoxic protein that specifically targets a class of receptors known as nicotinic acetylcholine receptors present in the nervous system.
