How Do You Spell KALLIDIN?

Pronunciation: [kˈalɪdˌɪn] (IPA)

The word "Kallidin" is spelled with a "k" instead of a "c" because it comes from the Greek word "kallikrein," which begins with a kappa sound. The pronunciation of "kallidin" is /kəˈlɪdɪn/ according to IPA phonetic transcription. The first syllable is stressed, and it's pronounced with a schwa sound followed by a clear "l" sound. The second syllable is pronounced with a short "i" sound, followed by a voiced "d" and a clear "ɪn" sound at the end.

KALLIDIN Meaning and Definition

1. Kallidin refers to a naturally occurring peptide in the human body that is part of the kinin family of peptides. It is derived from the cleavage of kininogen, a precursor protein present in the blood plasma. Kallidins are primarily responsible for promoting vasodilation and enhancing vascular permeability, thereby playing a crucial role in regulating blood pressure and fluid balance.

   Kallidin is produced through the enzymatic action of kallikreins, specifically tissue kallikrein, on kininogen. Once formed, it activates B1 and B2 kinin receptors, which are widely distributed throughout the body, to exert its biological effects. Through the B2 receptor, kallidin induces vasodilation by causing the relaxation of smooth muscle cells in blood vessels, leading to increased blood flow and reduced resistance in the vascular system. This mechanism contributes to the regulation of blood pressure.

   Furthermore, kallidin acts on endothelial cells to enhance vascular permeability, allowing plasma proteins and immune cells to enter tissues and facilitate appropriate inflammatory responses. This function is vital for initiating the proper immune response to injury or infection.

   Because of its potent vasodilatory and permeability-enhancing properties, kallidin is believed to be involved in various physiological and pathological processes, including inflammation, wound healing, and hypertension. Researchers continue to investigate the exact mechanisms by which kallidin operates and explore its potential therapeutic applications, particularly in cardiovascular disorders.

Common Misspellings for KALLIDIN

• jallidin
• mallidin
• lallidin
• oallidin
• iallidin
• kzllidin
• ksllidin
• kwllidin
• kqllidin
• kaklidin
• kaplidin
• kaolidin
• kalkidin
• kalpidin
• kaloidin
• kalludin
• kalljdin
• kallkdin
• kallodin
• kall9din

Etymology of KALLIDIN

The word "kallidin" is derived from the Greek word "kallikrein", which means "to separate into beautiful parts" or "to dissolve and separate". "Kallidin" specifically refers to a group of peptides that are formed by the enzymatic action of kallikrein on kininogen, a plasma protein. These peptides play a role in processes such as blood pressure regulation, inflammation, and pain transmission. The term "kallidin" was coined to describe these peptides by combining the Greek root "kalli-" (meaning beautiful) with the suffix "-din" (referring to their nature as kinin-like peptides).