ISOPROSTANES Meaning and
Definition
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Isoprostanes are a group of molecules that play a significant role in the body's oxidative stress response. They are a class of prostanoids, which are lipid compounds derived from arachidonic acid. Isoprostanes are formed through a non-enzymatic process involving the free radical-mediated peroxidation of arachidonic acid.
These molecules are generated in various tissues and can be detected in bodily fluids, such as blood and urine. Isoprostanes serve as reliable markers for assessing oxidative stress and lipid peroxidation, which are involved in several pathological conditions, including cardiovascular diseases, neurodegenerative disorders, and inflammation.
Isoprostanes have biological activities that resemble those of classic prostaglandins, which are important mediators of inflammation, pain, and fever. However, unlike prostaglandins, isoprostanes are not produced through enzymatic processes but rather as a consequence of oxidative damage to polyunsaturated fatty acids.
Measuring levels of isoprostanes in biological samples can provide valuable insights into the extent of oxidative stress occurring in the body. High levels of isoprostanes indicate increased oxidative damage, while low levels suggest a healthier oxidative balance. Therefore, quantifying isoprostanes is a useful tool for researchers and clinicians studying oxidative stress-related diseases and evaluating the effectiveness of therapeutic interventions.
In conclusion, isoprostanes are lipid compounds formed by the non-enzymatic peroxidation of arachidonic acid. They serve as reliable markers for assessing oxidative stress and lipid peroxidation, making them useful indicators of various pathological conditions.
Common Misspellings for ISOPROSTANES
- usoprostanes
- jsoprostanes
- ksoprostanes
- osoprostanes
- 9soprostanes
- 8soprostanes
- iaoprostanes
- izoprostanes
- ixoprostanes
- idoprostanes
- ieoprostanes
- iwoprostanes
- isiprostanes
- iskprostanes
- islprostanes
- ispprostanes
- is0prostanes
- is9prostanes
- isoorostanes
- isolrostanes
Etymology of ISOPROSTANES
The word "isoprostanes" is derived from the combination of "iso-" and "prostanes".
The prefix "iso-" in this context indicates "isomer", which means it is referring to compounds with the same molecular formula but different structural arrangements.
"Prostanes" refers to a family of compounds called prostaglandins, which are chemical substances involved in various physiological processes and are derived from fatty acids.
Therefore, "isoprostanes" can be understood as isomeric compounds related to prostaglandins or compounds structurally similar to prostaglandins. They are formed through the peroxidation of polyunsaturated fatty acids and are utilized as markers of oxidative stress in biological systems.
