ISOGENEIC TRANSPLANTATION Meaning and
Definition
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Isogeneic transplantation refers to a medical procedure in which organs, tissues, or cells are transferred from one genetically identical individual to another within the same species. In isogeneic transplantation, both the donor and recipient share a virtually identical genotype or genetic makeup, thereby minimizing the risk of rejection and immune responses.
This type of transplantation is particularly advantageous as it reduces the likelihood of graft-versus-host disease, a condition where the immune cells from the donor attack the recipient's tissues. Isogeneic transplantation also circumvents the need for immunosuppressant drugs, which are typically required to prevent rejection in allogeneic transplants.
Isogeneic transplantation is commonly utilized in experimental research and has proven to be an invaluable tool in studying various aspects of immunology, genetics, and tissue regeneration. By manipulating the genetics of the donor and recipient organisms, researchers can investigate the role of specific genes or immune molecules in transplantation outcomes.
However, the practical application of isogeneic transplantation in clinical settings is limited, as finding genetically identical donors within a human population is extremely rare. This restricts the use of isogeneic transplants to cases involving identical twins or close relatives with matching human leukocyte antigen (HLA) types. Nonetheless, isogeneic transplantation remains an essential technique in scientific investigations, providing crucial insights into the immune system and potential therapeutic approaches for transplantation-related diseases.
Common Misspellings for ISOGENEIC TRANSPLANTATION
- usogeneic transplantation
- jsogeneic transplantation
- ksogeneic transplantation
- osogeneic transplantation
- 9sogeneic transplantation
- 8sogeneic transplantation
- iaogeneic transplantation
- izogeneic transplantation
- ixogeneic transplantation
- idogeneic transplantation
- ieogeneic transplantation
- iwogeneic transplantation
- isigeneic transplantation
- iskgeneic transplantation
- islgeneic transplantation
- ispgeneic transplantation
- is0geneic transplantation
- is9geneic transplantation
- isofeneic transplantation
- isoveneic transplantation
Etymology of ISOGENEIC TRANSPLANTATION
The word "isogeneic transplantation" can be broken down into two parts: "isogeneic" and "transplantation".
1. Isogeneic: The term "isogeneic" comes from the prefix "iso-" meaning "equal" or "same", and the term "gene" referring to genes or genetic material. Therefore, "isogeneic" refers to individuals or organisms that have identical or highly similar genetic makeup.
2. Transplantation: The word "transplantation" comes from the Latin word "transplantare", which means "to transfer" or "to plant across". It refers to the process of transferring an organ, tissue, or cells from one organism (donor) to another organism (recipient).
When combined, "isogeneic transplantation" refers to the transfer of tissues, cells, or organs between genetically identical or highly similar individuals.
