ISOGENEIC HOMOGRAFTS Meaning and
Definition
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Isogeneic homografts, also known as syngeneic homografts, refer to the transplantation of tissues or organs between genetically identical individuals, such as identical twins or animals of the same inbred strain. The term "isogeneic" signifies that the donor and recipient share the same genetic makeup, thereby minimizing the risk of immune rejection and graft failure.
In the field of transplantation, isogeneic homografts are considered the gold standard for experimental studies and serve as an important tool in researching various aspects of immunology, biology, and pathology. Because the donor and recipient are genetically identical, there is no immunological mismatch, and the recipient's immune system does not recognize the transplanted tissue as foreign. This circumvents the need for immunosuppressive drugs, reducing complications associated with rejection and allowing for a more accurate evaluation of the transplanted tissue's function or the effects of certain treatments.
Isogeneic homografts have been widely employed in medical research to study graft survival, tissue rejection mechanisms, autoimmune diseases, and immunotherapy. They have played a crucial role in unraveling the intricate workings of the immune system, understanding the mechanisms underlying tissue rejection, and exploring novel therapeutic approaches.
Overall, isogeneic homografts offer a controlled experimental setting, where the impact of genetic factors and environmental variables can be precisely evaluated. They have proven invaluable in advancing our knowledge of transplantation biology and have paved the way for the development of safer and more effective transplantation procedures.
Common Misspellings for ISOGENEIC HOMOGRAFTS
- usogeneic homografts
- jsogeneic homografts
- ksogeneic homografts
- osogeneic homografts
- 9sogeneic homografts
- 8sogeneic homografts
- iaogeneic homografts
- izogeneic homografts
- ixogeneic homografts
- idogeneic homografts
- ieogeneic homografts
- iwogeneic homografts
- isigeneic homografts
- iskgeneic homografts
- islgeneic homografts
- ispgeneic homografts
- is0geneic homografts
- is9geneic homografts
- isofeneic homografts
- isoveneic homografts
Etymology of ISOGENEIC HOMOGRAFTS
The term "isogeneic homografts" is derived from two main components: "isogeneic" and "homografts".
1. Isogeneic: The term "isogeneic" is formed from two Greek roots - "iso" meaning "equal" or "same" and "genos" meaning "race" or "kind". The prefix "iso" signifies similarity or sameness, and "genos" refers to genetic origin or relatedness. Therefore, "isogeneic" refers to individuals or organisms that have a similar or identical genetic makeup, usually as a result of being derived from a common ancestor or lineage.
2. Homografts: The term "homografts" comes from two elements - "homo" and "graft".
