INOSINE PYROPHOSPHATE Meaning and
Definition
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Inosine Pyrophosphate (IPP) is a vital nucleotide derivative that plays a significant role in various biological processes. It is formed during the biosynthesis of purine nucleotides, primarily as a precursor molecule in the de novo synthesis pathway.
IPP is composed of the nitrogenous base inosine, which consists of a purine base adenine bound to a ribose sugar molecule via a glycosidic bond, and a pyrophosphate group. The pyrophosphate group is an anion formed by the release of two phosphate groups during the condensation of ATP molecules.
Inosine Pyrophosphate serves as an important intermediate in cellular metabolism. It acts as a key participant in the synthesis of adenosine triphosphate (ATP), the universal energy currency of cells. Additionally, IPP is involved in the production of deoxyribonucleotides, which are essential building blocks for DNA replication and cell division.
Moreover, Inosine Pyrophosphate plays a crucial role in regulating the activity of certain enzymes involved in purine metabolism. It acts as an allosteric effector for the enzyme IMP dehydrogenase, which catalyzes the conversion of inosine monophosphate (IMP) to xanthosine monophosphate (XMP).
Overall, Inosine Pyrophosphate is a key molecule in numerous cellular processes and biosynthetic pathways. Its involvement in purine nucleotide production, ATP synthesis, and enzymatic regulation underscores its importance in maintaining normal cellular functions.
Common Misspellings for INOSINE PYROPHOSPHATE
- unosine pyrophosphate
- jnosine pyrophosphate
- knosine pyrophosphate
- onosine pyrophosphate
- 9nosine pyrophosphate
- 8nosine pyrophosphate
- ibosine pyrophosphate
- imosine pyrophosphate
- ijosine pyrophosphate
- ihosine pyrophosphate
- inisine pyrophosphate
- inksine pyrophosphate
- inlsine pyrophosphate
- inpsine pyrophosphate
- in0sine pyrophosphate
- in9sine pyrophosphate
- inoaine pyrophosphate
- inozine pyrophosphate
- inoxine pyrophosphate
- inodine pyrophosphate
Etymology of INOSINE PYROPHOSPHATE
The word "inosine" is derived from the synthesis of the nucleoside inosine, which is composed of the nitrogenous base adenine and the sugar ribose. The base name "inos-" dates back to the early 20th century when it was mistakenly believed to be derived from muscle tissue where the nucleotide was first discovered. However, it was later identified that inosine is not specific to muscle tissue but rather found throughout the body.
The term "pyrophosphate" is composed of two parts: "pyro-" and "phosphate". "Pyro-" is derived from the Greek word "pyro" meaning "fire", indicating that it was initially thought to be formed from inorganic compounds subjected to intense heat. However, it was later discovered that "pyro-" in this context refers to the formation of a phosphodiester bond.
