HYPOCHROMATOSIS Meaning and
Definition
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Hypochromatosis is a medical condition characterized by the abnormal reduction or absence of normal coloration of cells, specifically red blood cells. It is a term used in the field of hematology to describe a group of genetic disorders that result in inadequate synthesis of hemoglobin, the protein responsible for carrying oxygen in the blood. The deficiency or malfunctioning of hemoglobin in individuals with hypochromatosis leads to a decrease in the red color of blood cells, resulting in their pale or hypochromic appearance under microscopic examination.
Hypochromatosis can be caused by various inherited mutations affecting the genes responsible for the synthesis of hemoglobin, such as HFE, ALAS2, and SLC25A37. Depending on the specific type of hypochromatosis, individuals may experience symptoms ranging from mild anemia and fatigue to more severe complications, including organ damage due to chronic iron overload.
Diagnosis of hypochromatosis typically involves a comprehensive medical history assessment, physical examination, blood tests, and genetic analysis to identify the underlying genetic mutation. Treatment options for hypochromatosis focus on managing its symptoms and complications. This may involve regular blood transfusions to correct anemia, iron chelation therapy to reduce iron overload, and occasionally, bone marrow transplant for certain cases.
In summary, hypochromatosis is a hereditary condition characterized by a decreased coloration of red blood cells due to deficiencies or malfunctions in hemoglobin synthesis. Its diagnosis involves a combination of clinical evaluation and genetic testing, and treatment aims to alleviate symptoms and manage complications associated with the disease.
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Nuclear solution, chromatolysis; the disappearance of chromatin, or of the nucleus, in a cell.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for HYPOCHROMATOSIS
- hypochromatosi3
- hypochromatosic
- hypochromatosiq
- hypochromatosir
- hypochromatteosis
- hypochromatwosis
- h ypochromatosis
- hypo chromatosis
- hypoc hromatosis
- hypoch romatosis
- hypochr omatosis
- hypochro matosis
- hypochrom atosis
- hypochroma tosis
- hypochromat osis
- hypochromato sis
- hypochromatos is
- hypochromatosi s
Etymology of HYPOCHROMATOSIS
The word hypochromatosis is derived from the combination of two Greek roots: hypo, meaning under or less than normal, and chroma, meaning color.
