HYDROXYLYSINE Meaning and
Definition
-
Hydroxylysine is a naturally occurring amino acid derivative that plays a crucial role in collagen synthesis within the human body. It is formed through the hydroxylation of the lysine amino acid, resulting in the addition of a hydroxyl group (-OH) to the lysine molecule. Hydroxylysine is found predominantly in collagen, the primary structural protein present in connective tissues such as bones, skin, tendons, and blood vessels.
The introduction of the hydroxyl group during collagen formation is fundamental for the stabilization and cross-linking of collagen molecules, contributing to the structure, strength, and function of these tissues. It enables the formation of strong intermolecular cross-links, enhancing the mechanical properties of collagen and promoting its stability and resistance to degradation.
Hydroxylysine exists in two isomeric forms: cis-hydroxylysine and trans-hydroxylysine. These isomers differ in the orientation of the hydroxyl group relative to the amino acid backbone and can have distinct functional properties.
Due to its importance in collagen synthesis, hydroxylysine serves as a key marker for monitoring collagen metabolism and turnover in various biological processes. Its measurement in biological samples, such as blood or urine, can provide valuable insights into the functioning of connective tissues and the presence of collagen-related disorders.
Common Misspellings for HYDROXYLYSINE
- gydroxylysine
- bydroxylysine
- nydroxylysine
- jydroxylysine
- uydroxylysine
- yydroxylysine
- htdroxylysine
- hgdroxylysine
- hhdroxylysine
- hudroxylysine
- h7droxylysine
- h6droxylysine
- hysroxylysine
- hyxroxylysine
- hycroxylysine
- hyfroxylysine
- hyrroxylysine
- hyeroxylysine
- hydeoxylysine
- hyddoxylysine
Etymology of HYDROXYLYSINE
The word "Hydroxylysine" is derived from the combination of two components: "Hydroxy" and "lysine".
1. "Hydroxy" is derived from the term "hydroxyl", which is a chemical group (-OH) consisting of one oxygen atom and one hydrogen atom. This group is typically attached to an organic compound, in this case, lysine.
2. "Lysine" refers to an essential amino acid, which is one of the building blocks of proteins. It was first isolated from casein (a milk protein) by the German chemist Ferdinand Heinrich Edmund Drechsel in 1889. The name "lysine" comes from the Greek word "lys" meaning "to loosen" or "release", as it was initially identified as a component that breaks down proteins during digestion.
