HLA BR Meaning and
Definition
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HLA BR stands for "Human Leukocyte Antigen-B27 Related" and refers to a genetically inherited protein that is present on the surface of human cells. HLA BR is a subtype of the Human Leukocyte Antigen (HLA) system, which plays a crucial role in the immune response and helps the immune system distinguish between self and foreign substances.
The HLA BR protein is encoded by a specific gene located on chromosome 6 in the Major Histocompatibility Complex (MHC) region. This protein is primarily found on the surface of white blood cells, particularly on immune cells known as T cells. HLA BR serves as a cell surface marker that helps the immune system recognize and interact with foreign antigens, such as viral or bacterial proteins.
The presence of HLA BR has been associated with several autoimmune diseases, such as ankylosing spondylitis, reactive arthritis, and certain forms of juvenile idiopathic arthritis. Individuals carrying the HLA-B27 gene have an increased risk of developing these conditions, although not all individuals with HLA BR will develop autoimmune diseases.
HLA BR testing is often conducted using molecular techniques to identify the specific genetic variant in an individual's DNA. This test can help in diagnosing certain autoimmune disorders and assessing the risk of developing related conditions. Proper understanding and interpretation of HLA BR test results require consultation with a medical professional or genetic counselor.
Common Misspellings for HLA BR
- gla br
- bla br
- nla br
- jla br
- ula br
- yla br
- hka br
- hpa br
- hoa br
- hlz br
- hls br
- hlw br
- hlq br
- hla vr
- hla nr
- hla hr
- hla gr
- hla be
- hla bd
- hla bf
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